Department of General Surgery and Urology, Jordan University of Science and Technology, Irbid, Jordan.
Department of Pathology and Microbiology, Jordan University of Science and Technology, Irbid, Jordan.
Am J Case Rep. 2021 Feb 8;22:e928548. doi: 10.12659/AJCR.928548.
BACKGROUND Osteoblastoma is a very rare bone tumor accounting for 1% of all bone tumors. Most of the time it involves the spine and long bones and it involves the ribs very rarely. While osteoblastoma occurrence in the first rib has been reported, causing neurogenic thoracic outlet syndrome (TOS) has never been reported. CASE REPORT A 23-year-old woman presented with a left cervical mass associated with pain and paresthesia in the medial aspect of the left upper extremity and 4th and 5th fingers for the previous 3 months. The patient denied any previous illness or trauma in her history. Physical examination revealed a hard mass in the posterior triangle of the left neck with altered sensation in the left 4th and 5th fingers. The patient was investigated by a chest roentgenogram, nerve conduction study, computer tomography (CT) of the chest, and magnetic resonance image (MRI), as well as incisional biopsy. Although all radiological investigations were suggesting osteochondroma with a differential diagnosis of chondrosarcoma, the incisional biopsy showed osteoblastoma. Radical surgical excision of the lesion followed through a left supraclavicular approach. The patient's preoperative symptoms were relieved completely and there was no recurrence of the tumor at 2 years. CONCLUSIONS Osteoblastoma of the first rib is very rare tumor and to present with TOS is extremely rare. The nonspecific radiological characteristics of the tumor, especially on CT, makes the preoperative certainty of the diagnosis unlikely.
骨母细胞瘤是一种非常罕见的骨肿瘤,占所有骨肿瘤的 1%。大多数情况下,它涉及脊柱和长骨,很少涉及肋骨。虽然已经报道了第一肋骨的骨母细胞瘤发生,但从未报道过引起神经性胸廓出口综合征(TOS)。
一名 23 岁女性因左颈前区肿块伴疼痛和左上肢内侧、第 4 指和第 5 指感觉异常就诊,病史为 3 个月。患者否认有任何既往疾病或外伤史。体格检查发现左颈后三角区有一硬肿块,左第 4 指和第 5 指感觉改变。患者进行了胸部 X 光、神经传导研究、胸部计算机断层扫描(CT)和磁共振成像(MRI)以及切开活检检查。尽管所有影像学检查均提示为骨软骨瘤,需与软骨肉瘤进行鉴别诊断,但切开活检显示为骨母细胞瘤。通过锁骨上入路进行了病变的根治性切除术。患者的术前症状完全缓解,2 年后肿瘤无复发。
第一肋骨的骨母细胞瘤是一种非常罕见的肿瘤,出现 TOS 极为罕见。肿瘤的非特异性影像学特征,特别是 CT,使得术前诊断的确定性不太可能。