Zoccali Carmine, Novello Mariangela, Arrigoni Francesco, Scotto di Uccio Alessandra, Attala Dario, Ferraresi Virginia
Oncological Orthopaedics Department, IRCCS-Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
Pathology Department, IRCCS-Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.
J Clin Med. 2021 Oct 10;10(20):4645. doi: 10.3390/jcm10204645.
osteoblastoma is a bone-forming tumor accounting for about 1% of all primary bone tumors and 3% of benign bone tumors. The gold-standard treatment is surgical excision; nevertheless, minimally invasive radiological techniques such as thermoablation and, more recently, high intensity focused ultrasound are gaining more importance. The aim of the present paper is to analyze surgical indications based on our experience and on the evidences in the literature.
all patients affected by osteoblastoma who underwent surgical excision in January 2009 and December 2018 were reviewed; eleven patients were enrolled in the study. The epidemiological aspects, size of the disease and site of onset, symptoms, surgery type, indications, and results are reported for every case.
all treatments were based on a preoperative diagnosis; pain was constant in all cases. Intralesional surgeries were performed in 9 out of 11 cases; the remaining 2 cases underwent wide resection. No early or late complications occurred after the surgical procedure. The indications for surgery were lesions very close to nerves or joints, unclear diagnosis, risk of fracture, lesion too large for radiofrequency thermoablation, or failure of minimally invasive treatments. At a medium follow-up of 88 months, no local recurrences were verified.
osteoblastoma is a rare tumor with difficult diagnosis. Identification is based on symptoms, imaging, and histology. When possible, minimally invasive techniques is preferred for treatment but surgery is still considered the gold standard.
骨母细胞瘤是一种成骨性肿瘤,约占所有原发性骨肿瘤的1%,良性骨肿瘤的3%。金标准治疗方法是手术切除;然而,热消融等微创放射技术,以及最近的高强度聚焦超声正变得越来越重要。本文的目的是根据我们的经验和文献证据分析手术指征。
回顾了2009年1月至2018年12月期间接受手术切除的所有骨母细胞瘤患者;11名患者纳入研究。报告了每个病例的流行病学情况、疾病大小和发病部位、症状、手术类型、指征和结果。
所有治疗均基于术前诊断;所有病例均有持续疼痛。11例中有9例行病灶内手术;其余2例行广泛切除。手术后未发生早期或晚期并发症。手术指征为病变非常靠近神经或关节、诊断不明确、有骨折风险、病变太大无法进行射频热消融或微创治疗失败。中位随访88个月时,未证实有局部复发。
骨母细胞瘤是一种罕见肿瘤,诊断困难。诊断基于症状、影像学和组织学。可能的话,治疗首选微创技术,但手术仍被视为金标准。