Jacobs J M, Goudswaard J
Tijdschr Diergeneeskd. 1977 Nov 1;102(21):1257-62.
Antisera to porcine immunoglobulins, conjugated with flurescein isothiocyanate, were used in studies on the localization of cells containing immunoglobulin in the tissues of the intestine and spleen in pigs. Cells containing IgM and IgA were found to be present in the lamina propria of the intestinal mucosa, the villous membrane showing fluorescence due to liberated immunoglobulins. Cells containing IgG and IgM were detected in the marginal areas of the splenic lymph nodes but could not be definitely identified as mature plasma cells.
将与异硫氰酸荧光素结合的猪免疫球蛋白抗血清用于研究猪肠道和脾脏组织中含免疫球蛋白细胞的定位。发现含IgM和IgA的细胞存在于肠黏膜固有层,由于释放的免疫球蛋白,绒毛膜呈现荧光。在脾淋巴结边缘区域检测到含IgG和IgM的细胞,但无法明确鉴定为成熟浆细胞。