Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.
Centre for Outcomes Research and Evaluation of the RI-MUHC, 5252 boul de Maisonneuve Ouest, Office 3E.09, Montreal, QC H4A 3S5, Canada.
Int J Environ Res Public Health. 2021 Feb 4;18(4):1454. doi: 10.3390/ijerph18041454.
Canada's largest national obstetric and diabetology organizations have recommended various algorithms for the screening of gestational diabetes mellitus (GDM) over the years. Though uniformity across recommendations from clinical practice guidelines (CPGs) is desirable, historically, national guidelines from Diabetes Canada (DC) and the Society of Obstetricians and Gynaecologists of Canada (SOGC) have differed. Lack of consensus has led to variation in screening approaches, rendering precise ascertainment of GDM prevalence challenging. To highlight the reason and level of disparity in Canada, we conducted a scoping review of CPGs released by DC and the SOGC over the last thirty years and distributed a survey on screening practices among Canadian physicians. Earlier CPGs were based on expert opinion, leading to different recommendations from these organizations. However, as a result of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study, disparities between DC and the SOGC no longer exist and many Canadian physicians have adopted their recent recommendations. Given that Canadian guidelines now recommend two different screening programs (one step vs. two step), lack of consensus on a single diagnostic threshold continues to exist, resulting in differing estimates of GDM prevalence. Our scoping review highlights these disparities and provides a step forward towards reaching a consensus on one unified threshold.
多年来,加拿大最大的产科和糖尿病学组织已经推荐了各种用于筛查妊娠糖尿病(GDM)的算法。虽然从临床实践指南(CPG)中获得一致的建议是理想的,但从历史上看,来自加拿大糖尿病协会(DC)和加拿大妇产科医生协会(SOGC)的国家指南有所不同。缺乏共识导致了筛查方法的差异,使得精确确定 GDM 的患病率具有挑战性。为了强调加拿大在这方面的原因和差异程度,我们对过去三十年 DC 和 SOGC 发布的 CPG 进行了范围综述,并对加拿大医生的筛查实践进行了调查。早期的 CPG 基于专家意见,导致这两个组织提出了不同的建议。然而,由于 Hyperglycemia and Adverse Pregnancy Outcome(HAPO)研究,DC 和 SOGC 之间的差异不再存在,许多加拿大医生已经采用了他们最近的建议。鉴于加拿大指南现在推荐了两种不同的筛查方案(一步法与两步法),对于单一诊断阈值仍缺乏共识,导致 GDM 患病率的估计值存在差异。我们的范围综述突出了这些差异,并朝着就单一统一阈值达成共识迈出了一步。