Clark P I, Slevin M L, Webb J A, Osborne R J, Jones S, Wrigley P F
Department of Medical Oncology, St. Bartholomew's Hospital, London, UK.
Br J Cancer. 1988 Mar;57(3):317-8. doi: 10.1038/bjc.1988.70.
Twenty patients with secondary liver tumours, predominantly from colorectal carcinoma, were treated with oral urea at a daily dose of 8 gm-2. Treatment was well tolerated without side-effects. No objective responses were seen. It is concluded that oral urea is ineffective in the treatment of liver metastases from colorectal cancer.
20例主要源自结直肠癌的继发性肝肿瘤患者接受了每日剂量为8克的口服尿素治疗。治疗耐受性良好，无副作用。未观察到客观反应。结论是口服尿素对治疗结直肠癌肝转移无效。
