Hooper T L, Rahman M, Magell J
Clin Oncol. 1984 Dec;10(4):341-4.
A consecutive series of 10 patients with hepatic metastases from colo-rectal carcinoma have been treated with oral urea. This substance has been reported to produce regression of hepatic secondaries from a variety of primary sources including colon. Although well tolerated, and leading to subjective improvement in some patients, no objective benefit has been confirmed from the treatment in this study.
对连续的10例结直肠癌肝转移患者采用口服尿素进行治疗。据报道,该物质可使包括结肠癌在内的多种原发肿瘤来源的肝脏继发性肿瘤消退。尽管耐受性良好,且部分患者有主观改善,但本研究中该治疗未证实有客观益处。