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用于非束缚状态下啮齿动物生物电位记录的电准静态动物体通信。

Electro-Quasistatic Animal Body Communication for Untethered Rodent Biopotential Recording.

机构信息

School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, 47906, USA.

Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47906, USA.

出版信息

Sci Rep. 2021 Feb 8;11(1):3307. doi: 10.1038/s41598-021-81108-8.

Abstract

Continuous multi-channel monitoring of biopotential signals is vital in understanding the body as a whole, facilitating accurate models and predictions in neural research. The current state of the art in wireless technologies for untethered biopotential recordings rely on radiative electromagnetic (EM) fields. In such transmissions, only a small fraction of this energy is received since the EM fields are widely radiated resulting in lossy inefficient systems. Using the body as a communication medium (similar to a 'wire') allows for the containment of the energy within the body, yielding order(s) of magnitude lower energy than radiative EM communication. In this work, we introduce Animal Body Communication (ABC), which utilizes the concept of using the body as a medium into the domain of untethered animal biopotential recording. This work, for the first time, develops the theory and models for animal body communication circuitry and channel loss. Using this theoretical model, a sub-inch[Formula: see text] [1″ × 1″ × 0.4″], custom-designed sensor node is built using off the shelf components which is capable of sensing and transmitting biopotential signals, through the body of the rat at significantly lower powers compared to traditional wireless transmissions. In-vivo experimental analysis proves that ABC successfully transmits acquired electrocardiogram (EKG) signals through the body with correlation [Formula: see text] when compared to traditional wireless communication modalities, with a 50[Formula: see text] reduction in power consumption.

摘要

连续的多通道生物电势信号监测对于理解整体人体至关重要,有助于神经研究中建立准确的模型和预测。目前,用于无束缚生物电势记录的无线技术的现状依赖于辐射电磁场(EM)。在这种传输中,由于 EM 场广泛辐射导致损耗效率低的系统,只有一小部分能量被接收。利用身体作为通信介质(类似于“电线”)可以将能量限制在身体内,从而产生比辐射 EM 通信低几个数量级的能量。在这项工作中,我们引入了动物体通信(ABC),它将使用身体作为介质的概念引入到无束缚动物生物电势记录领域。这项工作首次为动物体通信电路和信道损耗开发了理论和模型。使用这个理论模型,我们使用现成的组件构建了一个亚英寸[Formula: see text] [1 英寸×1 英寸×0.4 英寸]的定制传感器节点,与传统的无线传输相比,该节点能够以更低的功率通过大鼠的身体感知和传输生物电势信号。体内实验分析证明,与传统的无线通信方式相比,ABC 成功地通过身体传输了获取的心电图(EKG)信号,相关系数为[Formula: see text],同时功耗降低了 50[Formula: see text]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc7a/7870669/7db0c6c7e94f/41598_2021_81108_Fig1_HTML.jpg

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