Child Health Imprints (CHIL) Pte. Ltd, Singapore, Singapore.
Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea.
Sci Rep. 2021 Feb 8;11(1):3342. doi: 10.1038/s41598-021-82957-z.
Increased length of stay (LOS) in intensive care units is directly associated with the financial burden, anxiety, and increased mortality risks. In the current study, we have incorporated the association of day-to-day nutrition and medication data of the patient during its stay in hospital with its predicted LOS. To demonstrate the same, we developed a model to predict the LOS using risk factors (a) perinatal and antenatal details, (b) deviation of nutrition and medication dosage from guidelines, and (c) clinical diagnoses encountered during NICU stay. Data of 836 patient records (12 months) from two NICU sites were used and validated on 211 patient records (4 months). A bedside user interface integrated with EMR has been designed to display the model performance results on the validation dataset. The study shows that each gestation age group of patients has unique and independent risk factors associated with the LOS. The gestation is a significant risk factor for neonates < 34 weeks, nutrition deviation for < 32 weeks, and clinical diagnosis (sepsis) for ≥ 32 weeks. Patients on medications had considerable extra LOS for ≥ 32 weeks' gestation. The presented LOS model is tailored for each patient, and deviations from the recommended nutrition and medication guidelines were significantly associated with the predicted LOS.
重症监护病房(ICU)的住院时间延长与经济负担、焦虑和增加的死亡率直接相关。在本研究中,我们将患者在住院期间的日常营养和用药数据与预测的 LOS 相关联。为了证明这一点,我们开发了一个使用风险因素(a)围产期和产前详细信息,(b)营养和药物剂量与指南的偏差,以及(c)新生儿重症监护病房期间遇到的临床诊断来预测 LOS 的模型。使用来自两个新生儿重症监护病房的 836 名患者记录(12 个月)进行了研究,并在 211 名患者记录(4 个月)上进行了验证。床边用户界面与 EMR 集成在一起,用于在验证数据集上显示模型性能结果。研究表明,每个妊娠年龄组的患者都有与 LOS 相关的独特和独立的风险因素。妊娠是<34 周的新生儿的重要危险因素,<32 周的是营养偏差,≥32 周的是临床诊断(败血症)。接受药物治疗的患者的妊娠≥32 周的额外 LOS 相当可观。所提出的 LOS 模型针对每个患者进行了定制,并且营养和药物指南的偏差与预测的 LOS 显著相关。