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[冠状病毒大流行期间术前SARS-CoV-2检测结果]

[Results of preoperative SARS-CoV-2 testing in the coronavirus pandemic].

作者信息

Rassweiler-Seyfried M-C, Miethke T, Becker K-P, Siegel F

机构信息

Klinik für Urologie und Urochirurgie, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufter 1-3, 68161, Mannheim, Deutschland.

Institut für Medizinische Mikrobiologie und Hygiene, Universitätsmedizin Mannheim, Mannheim, Deutschland.

出版信息

Urologe A. 2021 Mar;60(3):331-336. doi: 10.1007/s00120-021-01459-y. Epub 2021 Feb 9.

DOI:10.1007/s00120-021-01459-y
PMID:33559693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7871307/
Abstract

BACKGROUND

Surgery is challenging during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to investigate the preoperative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in elective and emergency surgery and to calculate the patient contacts during hospital stay.

MATERIALS AND METHODS

All surgeries defined by the German procedural classification (starting with a 5) from 1 June until 29 November 2020 were retrospectively evaluated regarding the preoperative SARS-CoV‑2 nasopharyngeal swab test. The results were then divided in emergency and elective surgeries. To show the personal contacts of the patients in a university hospital, we calculated the patient pathway within the department of urology and urosurgery for April 2020. Therefor we used the electronic patient records.

RESULTS

Altogether 7745 surgical procedures in 5985 patients were performed, whereby 39 (0.5%) SARS-CoV‑2 tests were positive. 2833 (37%) surgical procedures were emergency cases and 4912 (63%) were elective procedures. 25 (0.9%) of the emergency group and 14 (0.3%) of the elective surgeries had a positive SARS-CoV‑2 test. The average number of contacts in the patient room was 12.83 (0-50) and 84.22 (0-249) at the ward level, not counting contacts with the clinic staff.

CONCLUSIONS

Nearly 1% of the preoperative SARS-CoV‑2 tests of either emergency or elective surgeries tested positive in the 6 months prior to November 2020. Although the risk of undetected SARS-CoV‑2 infection appears to be low in terms of costs and personnel, preoperative screening is useful in high-risk areas to ensure further necessary surgeries, especially concerning cancer patients and to prevent virus spread in a hospital.

摘要

背景

在2019年冠状病毒病(COVID-19)大流行期间,手术具有挑战性。本研究旨在调查择期手术和急诊手术术前严重急性呼吸综合征冠状病毒2(SARS-CoV-2)检测情况,并计算患者住院期间的接触人数。

材料与方法

回顾性评估2020年6月1日至11月29日德国程序分类(以5开头)定义的所有手术的术前SARS-CoV-2鼻咽拭子检测情况。结果分为急诊手术和择期手术。为了展示大学医院患者的个人接触情况,我们计算了2020年4月泌尿外科和泌尿外科学科内的患者路径。为此我们使用了电子病历。

结果

共对5985例患者进行了7745例外科手术,其中39例(0.5%)SARS-CoV-2检测呈阳性。2833例(37%)外科手术为急诊病例,4912例(63%)为择期手术。急诊组25例(0.9%)和择期手术14例(0.3%)的SARS-CoV-2检测呈阳性。不计算与临床工作人员的接触,病房内患者的平均接触人数为12.83(0 - 50),科室层面为84.22(0 - 249)。

结论

在2020年11月前的6个月中,急诊或择期手术术前SARS-CoV-2检测近1%呈阳性。尽管从成本和人员方面来看,未检测到SARS-CoV-2感染的风险似乎较低,但术前筛查在高风险地区有助于确保进一步的必要手术,特别是对于癌症患者,并防止病毒在医院传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b47/7871307/7d860f6a5fd3/120_2021_1459_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b47/7871307/cb1e534b6423/120_2021_1459_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b47/7871307/7d860f6a5fd3/120_2021_1459_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b47/7871307/cb1e534b6423/120_2021_1459_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b47/7871307/7d860f6a5fd3/120_2021_1459_Fig2_HTML.jpg

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本文引用的文献

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Br J Surg. 2021 Jan 27;108(1):88-96. doi: 10.1093/bjs/znaa051.
2
Mandatory preoperative COVID-19 testing for cancer patients-Is it justified?癌症患者术前进行 COVID-19 检测是否合理?
J Surg Oncol. 2020 Dec;122(7):1288-1292. doi: 10.1002/jso.26187. Epub 2020 Aug 25.
3
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.
围手术期 SARS-CoV-2 感染患者的死亡率和肺部并发症:一项国际队列研究。
Lancet. 2020 Jul 4;396(10243):27-38. doi: 10.1016/S0140-6736(20)31182-X. Epub 2020 May 29.
4
Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection.新型冠状病毒肺炎感染潜伏期接受手术患者的临床特征及预后
EClinicalMedicine. 2020 Apr 5;21:100331. doi: 10.1016/j.eclinm.2020.100331. eCollection 2020 Apr.