Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Arch Orthop Trauma Surg. 2021 Mar;141(3):461-468. doi: 10.1007/s00402-021-03791-6. Epub 2021 Feb 9.
It is essential to exclude a periprosthetic joint infection (PJI) prior to revision surgery. It is recommended to routinely aspirate the joint before surgery. However, this may not be necessary in a subgroup of patients. The aim of our study was to investigate if specific clinical and implant characteristics could be identified to rule out a PJI prior to revision surgery.
We retrospectively evaluated clinical and implant characteristics of patients who underwent a hip or knee revision surgery between October 2015 and October 2018. Patients were diagnosed with a PJI according to the MSIS diagnostic criteria.
A total of 156 patients were analyzed, including 107 implants that were revised because of prosthetic loosening and 49 because of mechanical failure (i.e. instability, malalignment or malpositioning). No PJI was diagnosed in the group with mechanical failure. In the prosthetic loosening group, 20 of 107 were diagnosed with a PJI (19%). Although there was a significantly lower chance of having a PJI with an implant age of > 5 years combined with a CRP < 5 mg/L, an infection was still present in 3 out of 39 cases (8%).
Implants with solely mechanical failure without signs of loosening and low inflammatory parameters probably do not require a synovial fluid aspiration. These results need to be confirmed in a larger cohort of patients. In case of prosthetic loosening, all joints need to be aspirated before surgery as no specific characteristic could be identified to rule out an infection.
在进行翻修手术前,排除假体周围关节感染(PJI)至关重要。建议在手术前常规抽吸关节液,但对于某些亚组患者,这可能并非必要。本研究旨在探讨是否可以确定特定的临床和植入物特征,以在翻修手术前排除 PJI。
我们回顾性评估了 2015 年 10 月至 2018 年 10 月期间接受髋关节或膝关节翻修手术的患者的临床和植入物特征。根据 MSIS 诊断标准,患者被诊断为 PJI。
共分析了 156 例患者,其中 107 例因假体松动而翻修,49 例因机械故障(即不稳定、对线不良或定位不当)而翻修。在机械故障组中未诊断出 PJI。在假体松动组中,107 个假体中有 20 个(19%)被诊断为 PJI。尽管植入物年龄>5 年且 CRP<5mg/L 时,发生 PJI 的可能性显著降低,但在 39 例中有 3 例(8%)仍存在感染。
无松动迹象且炎症参数较低的单纯机械故障植入物可能不需要关节液抽吸。这些结果需要在更大的患者队列中得到证实。在假体松动的情况下,所有关节在手术前都需要抽吸,因为无法确定排除感染的特定特征。