College of Atmospheric Sciences, Key Laboratory of Semi-Arid Climate Change, Ministry of Education, Lanzhou University, Lanzhou, 730000, China.
The Second Hospital, Lanzhou University, Lanzhou, 730000, China.
Environ Geochem Health. 2021 Sep;43(9):3457-3468. doi: 10.1007/s10653-021-00837-x. Epub 2021 Feb 9.
Epidemiological studies have suggested that particulate matter (PM) pollution seriously affects human health, particularly it is closely associated with respiratory diseases. The aim of this study is to quantitatively evaluate the effect of PMs (PM and PM) on emergency room (ER) visits for respiratory diseases in Lanzhou, a valley basin city in northwest China. Based on the data of the ER visits, daily concentration of particulate matters and daily meteorological elements from January 1, 2013, to July 31, 2017, we used a generalized additive model (GAM) of time series to evaluate the exposure-response relationship between PMs and respiratory ER visits. Seasonal modified effects of PM and PM on different age and gender groups were also performed. Results showed that the highest incidence of respiratory diseases occurred in winter. Respiratory ER visits for the total were significantly associated with PM (at lag 0 day) and PM (at lag 3 days), with relative risks (RRs) of 1.042 (95%CI: 1.036 -1.047) and 1.013 (95%CI: 1.011-1.016), respectively. Effects of PM pollutants on respiratory diseases are different among different age and gender groups. Children under 15 years and the elders over 60 years were the most sensitive to PM pollution, and males were more sensitive than females. The results obtained in the current study would provide a scientific evidence for local government to make policy decision for prevention of respiratory diseases.
流行病学研究表明,颗粒物(PM)污染严重影响人类健康,特别是与呼吸道疾病密切相关。本研究旨在定量评估 PM(PM 和 PM)对中国西北山谷盆地城市兰州呼吸道疾病急诊就诊的影响。基于 2013 年 1 月 1 日至 2017 年 7 月 31 日的急诊就诊数据、每日颗粒物浓度和每日气象要素数据,我们使用时间序列广义相加模型(GAM)评估了 PM 与呼吸道急诊就诊之间的暴露-反应关系。还对不同年龄和性别组的 PM 和 PM 的季节性修正效应进行了分析。结果表明,呼吸道疾病的高发期出现在冬季。总呼吸道急诊就诊与 PM(lag0 天)和 PM(lag3 天)显著相关,相对风险(RR)分别为 1.042(95%CI:1.036-1.047)和 1.013(95%CI:1.011-1.016)。PM 污染物对呼吸道疾病的影响在不同年龄和性别组之间存在差异。15 岁以下儿童和 60 岁以上老年人对 PM 污染最为敏感,男性比女性更为敏感。本研究的结果将为当地政府制定预防呼吸道疾病的政策决策提供科学依据。