School of Public Health and Zoonoses, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India.
Environ Sci Pollut Res Int. 2021 Jun;28(23):29455-29466. doi: 10.1007/s11356-020-12057-4. Epub 2021 Feb 9.
Antibiotics are frequently used in the dairy sector for prophylactic uses along with therapeutic purposes. Throughout the globe, antibiotic resistance has turned out as one of the greatest public health issue with greater concern in developing countries, such as India. On the matrix wise comparison of the study, slurry samples in all three farming systems show the highest proportion of positive samples. Out of 153 slurry samples, 15.6% samples showed the presence of antibiotic residues. Eighteen milk samples (11.7%) showed the presence of residues following this trend. Only one sample (0.65%) was positive of animal drinking water in the study. None of the targeted residues were found in any sample of human drinking water. The four pond water samples showed the prevalence of residues of oxytetracycline (2 samples) and enrofloxacin (2 samples). Medium size farms (10-30 animals) comprised comparative higher levels than small (< 10) and large farms (> 30). The excretion mass modelling of antibiotics released in the environment indicated 8325.41 kg of oxytetracycline and 12,498.89 kg of enrofloxacin per year. The study helps in providing understanding in the relation between antibiotics usage and dissemination of their residues to the environment which may result in likely ecotoxicological consequences.
抗生素在奶牛养殖中常被用作预防和治疗用途。在全球范围内，抗生素耐药性已成为最大的公共卫生问题之一，在印度等发展中国家尤为令人关注。就研究的矩阵比较而言，所有三种养殖系统的粪浆样本显示出阳性样本的比例最高。在 153 个粪浆样本中，有 15.6%的样本显示存在抗生素残留。按照这种趋势，有 18 个牛奶样本（11.7%）显示存在残留。在研究中，只有一个动物饮用水样本（0.65%）呈阳性。在任何一个人饮用水样本中都没有发现目标残留。四个池塘水样显示出土霉素（2 个样本）和恩诺沙星（2 个样本）残留的流行。中规模农场（10-30 头动物）的含量比小规模（<10 头）和大规模农场（>30 头）更高。抗生素在环境中的释放排泄质量模型表明，每年有 8325.41 千克土霉素和 12498.89 千克恩诺沙星被释放到环境中。该研究有助于了解抗生素使用与抗生素残留向环境传播之间的关系，这可能导致潜在的生态毒理学后果。
