Griffin C A, Long P P, Schachat A P
Johns Hopkins Onocology Center, Baltimore, MD 21205.
Cancer Genet Cytogenet. 1988 May;32(1):129-32. doi: 10.1016/0165-4608(88)90319-6.
Chromosome analysis of short-term culture of melanoma cells from a choroidal melanoma showed a karyotype of 46,XY, -21, +t(6p21q). Trisomy 6p has been observed in cutaneous melanomas; this case suggests that chromosome abnormalities in ocular melanomas may be similar to those from cutaneous melanoma.
对脉络膜黑色素瘤的黑色素瘤细胞进行短期培养后的染色体分析显示，其核型为46,XY, -21, +t(6p21q)。在皮肤黑色素瘤中已观察到6号染色体短臂三体；该病例表明，眼内黑色素瘤的染色体异常可能与皮肤黑色素瘤相似。
