一例转移至脑部的人类恶性黑色素瘤的细胞遗传学发现。
Cytogenetic findings in a human malignant melanoma metastatic to the brain.
作者信息
Rey J A, Bello M J, de Campos J M, Ramos M C, Benítez J
出版信息
Cancer Genet Cytogenet. 1985 Mar 15;16(2):179-83. doi: 10.1016/0165-4608(85)90013-5.
PMID:3855692
Abstract
Cytogenetic analysis by G-banding of direct and preparations of a malignant melanoma metastatic to the brain in vitro showed a pseudodiploid modal chromosome number, including five marker chromosomes, one of which was an i(6p). These results agree with those recently reported about the preferential involvement of chromosome #6 in malignant melanoma.
摘要
通过G显带对体外转移至脑的恶性黑色素瘤的直接标本和制备物进行细胞遗传学分析，结果显示假二倍体众数染色体数，包括5条标记染色体，其中一条是i(6p)。这些结果与最近报道的关于6号染色体在恶性黑色素瘤中优先受累的情况相符。
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