短信提醒对哮喘患者吸入治疗依从性的有效性：前瞻性多中心随机临床试验
Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial.
作者信息
Almonacid Carlos, Melero Carlos, López Viña Antolín, Cisneros Carolina, Pérez de Llano Luis, Plaza Vicente, García-Rivero Juan Luis, Romero Falcón Auxiliadora, Ramos Jacinto, Bazús González Teresa, Andrés Prado María, Muriel Alfonso
机构信息
Department of Respiratory Medicine, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcala de Henares, Madrid, Spain.
Department of Respiratory Medicine, Hospital Universitario 12 de Octubre, Institute for Health Research (i+12), Complutense University of Madrid, Madrid, Spain.
出版信息
JMIR Form Res. 2021 Feb 9;5(2):e12218. doi: 10.2196/12218.
BACKGROUND
Poor adherence to inhaled medication in asthma patients is of great concern. It is one of the main reasons for inadequate asthma control.
OBJECTIVE
The goal of the research was to determine if motivational messages using short message service (SMS, or text) improved adherence to inhaled medication in patients with asthma.
METHODS
A prospective multicenter randomized parallel-group clinical trial was conducted in 10 asthma clinics in Spain. Adherence was assessed with electronic monitors (Smartinhaler, Adherium Ltd) connected to inhalers. Patients in the SMS group received psychologist-developed motivational messages every 3 days for 6 months.
RESULTS
There were 53 patients in the SMS group and 88 patients in the control group. After 6 months, mean electronic adherence was 70% (SD 17%) in the intervention group and 69% (SD 17%) in the control group (P=.82). Significant differences between the study groups in morning and evening adherence to inhaled therapy, asthma control, exhaled nitric oxide levels, or improvement of lung functions were not observed.
CONCLUSIONS
Motivational messages were not useful to improve adherence to inhaled asthma medication compared with usual care.
背景
哮喘患者对吸入药物的依从性差是一个备受关注的问题。这是哮喘控制不佳的主要原因之一。
目的
本研究的目的是确定使用短信服务（SMS，或文本）发送的激励信息是否能提高哮喘患者对吸入药物的依从性。
方法
在西班牙的10家哮喘诊所进行了一项前瞻性多中心随机平行组临床试验。通过连接到吸入器的电子监测器（Smartinhaler，Adherium Ltd）评估依从性。短信组的患者每3天接收一次由心理学家编写的激励信息，持续6个月。
结果
短信组有53名患者，对照组有88名患者。6个月后，干预组的平均电子依从率为70%（标准差17%），对照组为69%（标准差17%）（P = 0.82）。在早晚吸入治疗的依从性、哮喘控制、呼出一氧化氮水平或肺功能改善方面，研究组之间未观察到显著差异。
结论
与常规护理相比，激励信息对提高哮喘吸入药物的依从性并无帮助。
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