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[考虑抗生素管理的腔内泌尿外科手术抗生素预防]

[Antibiotic prophylaxis for endourological interventions considering antibiotic stewardship].

作者信息

Kranz Jennifer, Schneidewind Laila, Pilatz Adrian, Wagenlehner Flo Ri An

机构信息

Klinik für Urologie und Kinderurologie, St.-Antonius-Hospital gGmbH, Akademisches Lehrkrankenhaus der RWTH Aachen, Dechant-Deckers-Str. 8, 52249, Eschweiler, Deutschland.

Universitätsklinik und Poliklinik für Urologie, Universitätsklinikum Halle (Saale), Halle (Saale), Deutschland.

出版信息

Urologe A. 2021 Mar;60(3):383-392. doi: 10.1007/s00120-021-01455-2. Epub 2021 Feb 9.

Abstract

Perioperative antibiotic prophylaxis in endourology is used to reduce or avoid postoperative surgical site infections and complicated urinary tract infections. Special attention is paid to antibiotic stewardship strategies to avoid the continuing selection of antibiotics and multidrug-resistant uropathogens as well as collateral damage to the microbiome. The individual risk profile, the local resistance situation, the expected pathogen spectrum, the pharmacokinetics and the approval of each substance are important aspects to be considered in the indications and selection of perioperative antibiotic prophylaxis. Furthermore, applicable hygiene regulations and the surgical care of an intervention must be observed.

摘要

腔内泌尿外科手术围手术期抗生素预防用于减少或避免术后手术部位感染和复杂性尿路感染。特别关注抗生素管理策略,以避免持续选择抗生素和多重耐药尿路病原体,以及对微生物群的附带损害。个体风险状况、当地耐药情况、预期病原体谱、每种药物的药代动力学和批准情况是围手术期抗生素预防适应症和选择中需要考虑的重要方面。此外,必须遵守适用的卫生法规和手术干预的护理要求。

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