Suppr超能文献

神经功能障碍患者胃造瘘术后的并发症。

Complications in patients with neurological impairment after gastrostomy.

机构信息

Department of Pediatric Surgery, Kurume University School of Medicine, Fukuoka, Japan.

Department of Pediatric, National Hospital Organization Higashisaga Hospital, Higashiomi, Japan.

出版信息

Pediatr Int. 2021 Nov;63(11):1357-1362. doi: 10.1111/ped.14645. Epub 2021 Oct 5.

Abstract

BACKGROUND

Neurological impairment (NI) is responsible for most conditions that require a permanent gastrostomy tube. The present study assessed the occurrence of short- and long-term complications after video-assisted gastrostomy (VAG) in patients with NI.

METHODS

The incidence of short- (<6 months) and long-term (over 2 years) complications of VAG were analyzed in a retrospective study. The differences between the incidence of the complications of VAG according to the age at surgery (≤15 years vs. ≥16 years) were also evaluated. The short- and long-term complications observed were granulation tissue formation, infection requiring antibiotic treatment, skin problems, perigastrostomy leakage, vomiting, accidental tube dislodgement, dumping syndrome, ileus, and peritonitis.

RESULTS

Eighty-two patients were evaluated for short- and long-term complications. The long-term complication rate was significantly lower than the short-term complication rate (P = 0.0026). Onodera's prognostic nutritional index before VAG in patients with long-term complications was significantly lower than in patients without such complications (P = 0.046). The incidence of long-term granulation tissue formation, infection, and vomiting were significantly lower than those of similar short-term complications. Long-term skin problems were associated with short-term skin problems (odds ratio: 18.95; 95% confidence interval: 4.53-92.98; P < 0.001). The number of patients ≥16 years old with short- and long-term skin problems was significantly higher than in patients ≤15 years old (P = 0.0014 and P = 0.0073, respectively).

CONCLUSIONS

The incidence rate of granulation tissue formation and infection after VAG were lower in the long term than in the short term. However, patients ≥16 years old presented with persistent complications.

摘要

背景

神经损伤(NI)是导致大多数需要永久性胃造口管的情况的原因。本研究评估了视频辅助胃造口术(VAG)后 NI 患者短期和长期并发症的发生情况。

方法

回顾性研究分析了 VAG 短期(<6 个月)和长期(>2 年)并发症的发生率。还评估了手术年龄(≤15 岁与≥16 岁)对 VAG 并发症发生率的影响。观察到的短期和长期并发症包括肉芽组织形成、需要抗生素治疗的感染、皮肤问题、胃造口周围漏、呕吐、意外管脱落、倾倒综合征、肠梗阻和腹膜炎。

结果

82 例患者评估了短期和长期并发症。长期并发症发生率明显低于短期并发症发生率(P=0.0026)。长期并发症患者的 VAG 前小野寺预后营养指数明显低于无此类并发症的患者(P=0.046)。长期肉芽组织形成、感染和呕吐的发生率明显低于类似的短期并发症。长期皮肤问题与短期皮肤问题有关(比值比:18.95;95%置信区间:4.53-92.98;P<0.001)。≥16 岁的患者中,短期和长期皮肤问题的患者数量明显高于≤15 岁的患者(P=0.0014 和 P=0.0073)。

结论

与短期相比,VAG 后肉芽组织形成和感染的发生率在长期内较低。然而,≥16 岁的患者存在持续性并发症。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验