Med Sci Sports Exerc. 2021 May 1;53(5):1041-1049. doi: 10.1249/MSS.0000000000002561.
The acute effects of a single bout of upper-body exercise on postprandial metabolism in persons with spinal cord injury are currently not well understood. The primary aim of this study was to evaluate the effects of a single bout of upper-body high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) in comparison with a no-exercise control (REST) condition on postprandial metabolic responses in persons with chronic paraplegia.
Ten participants (eight males, two females; age, 49 ± 10 yr; time since injury, 22 ± 13 yr) with chronic paraplegia took part in a randomized crossover study, consisting of three trials: HIIE (8 × 60 s at 70% peak power output [PPEAK]), MICE (25 min at 45% PPEAK), and REST, at least 3 d apart. Exercise was performed in the fasted state, and participants consumed a mixed-macronutrient liquid meal 1-h postexercise. Venous blood and expired gas samples were collected at regular intervals for 6-h postmeal consumption.
There were no significant differences in postprandial incremental area under the curve for triglycerides (P = 0.59) or glucose (P = 0.56) between conditions. Insulin incremental area under the curve tended to be lower after MICE (135 ± 85 nmol·L-1 per 360 min) compared with REST (162 ± 93 nmol·L-1 per 360 min), but this did not reach statistical significance (P = 0.06, d = 0.30). Participants reported a greater fondness (P = 0.04) and preference for HIIE over MICE.
After an overnight fast, a single bout of upper-body exercise before eating has no effect on postprandial metabolism in persons with chronic paraplegia, irrespective of exercise intensity. This suggests that alternative exercise strategies may be required to stimulate postprandial substrate oxidation for this population.
目前人们对于单次上半身运动对脊髓损伤后餐后代谢的急性影响还不太了解。本研究的主要目的是评估单次上半身高强度间歇运动（HIIE）和中等强度持续运动（MICE）与不运动对照（REST）条件对慢性截瘫患者餐后代谢反应的影响。
10 名参与者（8 名男性，2 名女性；年龄，49 ± 10 岁；受伤后时间，22 ± 13 年）参加了一项随机交叉研究，包括三个试验：HIIE（8×60s，70%峰值功率输出[PPEAK]）、MICE（25min，45%PPEAK）和 REST，至少间隔 3 天。运动在空腹状态下进行，参与者在运动后 1 小时内摄入混合宏量营养素的液体餐。在餐后 6 小时内定期采集静脉血和呼出气体样本。
在餐后甘油三酯（P=0.59）或葡萄糖（P=0.56）的增量曲线下面积方面，三种条件之间没有显著差异。与 REST（360 分钟内 162±93nmol·L-1）相比，MICE 后胰岛素增量曲线下面积有降低的趋势（360 分钟内 135±85nmol·L-1），但未达到统计学意义（P=0.06，d=0.30）。参与者报告说，与 MICE 相比，他们更喜欢 HIIE（P=0.04）。
在隔夜禁食后，进食前进行单次上半身运动对慢性截瘫患者的餐后代谢没有影响，无论运动强度如何。这表明，对于这一人群，可能需要其他的运动策略来刺激餐后底物氧化。
