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2
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本文引用的文献

1
Vaping Associated Lung Injury (EVALI): An Explosive United States Epidemic.电子烟相关肺损伤(EVALI):美国的一场爆发性流行病。
Mo Med. 2019 Nov-Dec;116(6):492-496.
2
Syndromic Surveillance for E-Cigarette, or Vaping, Product Use-Associated Lung Injury.电子烟或雾化产品使用相关肺损伤的症状监测
N Engl J Med. 2020 Feb 20;382(8):766-772. doi: 10.1056/NEJMsr1915313. Epub 2019 Dec 20.
3
Characteristics of Hospitalized and Nonhospitalized Patients in a Nationwide Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injury - United States, November 2019.在全国范围内爆发的电子烟或蒸气产品使用相关肺损伤的住院和非住院患者的特征 - 美国,2019 年 11 月。
MMWR Morb Mortal Wkly Rep. 2019 Nov 22;68(46):1076-1080. doi: 10.15585/mmwr.mm6846e1.
4
Clinical presentation, treatment, and short-term outcomes of lung injury associated with e-cigarettes or vaping: a prospective observational cohort study.与电子烟或蒸气相关的肺损伤的临床表现、治疗和短期结局:一项前瞻性观察性队列研究。
Lancet. 2019 Dec 7;394(10214):2073-2083. doi: 10.1016/S0140-6736(19)32679-0. Epub 2019 Nov 8.
5
Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury - United States, October 2019.更新:美国 2019 年 10 月,医疗保健提供者评估和护理疑似电子烟或蒸气产品使用相关肺损伤患者的临时指南。
MMWR Morb Mortal Wkly Rep. 2019 Oct 18;68(41):919-927. doi: 10.15585/mmwr.mm6841e3.
6
Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Final Report.伊利诺伊州和威斯康星州与电子烟使用相关的肺部疾病-最终报告。
N Engl J Med. 2020 Mar 5;382(10):903-916. doi: 10.1056/NEJMoa1911614. Epub 2019 Sep 6.
7
Acute eosinophilic pneumonia following electronic cigarette use.使用电子烟后发生的急性嗜酸性粒细胞性肺炎。
Respir Med Case Rep. 2019 Mar 18;27:100825. doi: 10.1016/j.rmcr.2019.100825. eCollection 2019.
8
E-Cigarette Chemistry and Analytical Detection.电子烟化学与分析检测。
Annu Rev Anal Chem (Palo Alto Calif). 2019 Jun 12;12(1):23-39. doi: 10.1146/annurev-anchem-061318-115329. Epub 2019 Mar 8.
9
Vital Signs: Tobacco Product Use Among Middle and High School Students - United States, 2011-2018.生命体征:2011-2018 年美国中学生和高中生的烟草制品使用情况。
MMWR Morb Mortal Wkly Rep. 2019 Feb 15;68(6):157-164. doi: 10.15585/mmwr.mm6806e1.
10
Prevalence of Cannabis Use in Electronic Cigarettes Among US Youth.美国青年电子烟使用的流行率。
JAMA Pediatr. 2018 Nov 1;172(11):1097-1099. doi: 10.1001/jamapediatrics.2018.1920.

电子烟与雾化产品使用相关的肺损伤:青少年病例系列

E-cigarettes and Vaping, Product-use Associated Lung Injury: A Case Series of Adolescents.

作者信息

Khan Abdullah, Parlette Karli, Kuntz Heather M

机构信息

Loma Linda University, Department of emergency medicine, Loma Linda, California.

Loma Linda University, Department of Emergency Medicine, Loma Linda, California.

出版信息

Clin Pract Cases Emerg Med. 2021 Feb;5(1):11-16. doi: 10.5811/cpcem.2020.10.48707.

DOI:10.5811/cpcem.2020.10.48707
PMID:33560943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7872611/
Abstract

INTRODUCTION

Lung injury associated with the use of electronic cigarettes and vaping (EVALI) was first identified in 2019. Since then, clusters of cases have been reported in the literature. Our aim was to describe the clinical presentation of adolescents with EVALI in the emergency department and their clinical outcomes.

CASE SERIES

In our case series, we identified seven adolescents diagnosed with EVALI. We describe their signs and symptoms on presentation to the emergency department and their clinical course. The most common symptoms on presentation were cough, shortness of breath, and vomiting. Each of these symptoms was seen in 71% of patients (n = 5), although not always together. Sinus tachycardia was noticed in 100% of patients (n = 7) and tachypnea in 85% (n = 6). While 85% (n = 6) required hospitalization for respiratory support, all patients were later discharged home on room air. After the diagnosis of EVALI, 85% of patients (n = 6) were treated with steroids.

CONCLUSION

EVALI is a new disease with unclear mechanisms that commonly presents with symptoms of cough, shortness of breath, and vomiting. It causes severe respiratory compromise in the adolescent population, requiring hospitalization and respiratory support.

摘要

引言

与使用电子烟和雾化相关的肺损伤(EVALI)于2019年首次被发现。从那时起,文献中陆续报道了多例病例。我们的目的是描述急诊科中患有EVALI的青少年的临床表现及其临床结局。

病例系列

在我们的病例系列中,我们确定了7名被诊断为EVALI的青少年。我们描述了他们在急诊科就诊时的体征和症状以及他们的临床病程。就诊时最常见的症状是咳嗽、呼吸急促和呕吐。这些症状在71%的患者(n = 5)中出现,不过并非总是同时出现。100%的患者(n = 7)出现窦性心动过速,85%(n = 6)出现呼吸急促。85%(n = 6)的患者需要住院接受呼吸支持,所有患者后来均在室内空气中呼吸的情况下出院回家。在诊断为EVALI后,85%的患者(n = 6)接受了类固醇治疗。

结论

EVALI是一种机制不明的新疾病,通常表现为咳嗽、呼吸急促和呕吐等症状。它会导致青少年出现严重的呼吸功能不全,需要住院和呼吸支持。