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Evidence for in situ amplification of a germ line homogeneously staining region in the mouse.

作者信息

Boldyreff B, Winking H, Weith A, Traut W

机构信息

Institut für Biologie, Medizinische Universität zu Lübeck, F.R. Germany.

出版信息

Cytogenet Cell Genet. 1988;47(1-2):84-5. doi: 10.1159/000132512.

Abstract

A cloned DNA sequence that is specific for a germ line homogeneously staining region (HSR) on chromosome 1 of the mouse was found to be homologous to a single copy sequence in non-HSR mice. By in situ hybridization, the sequence in non-HSR mice was localized to approximately the same site as the insertion site of the HSR on chromosome 1 of HSR mice, indicating in situ amplification of the HSR.

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