Mercy Perinatal, Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Heidelberg, Australia.
J Matern Fetal Neonatal Med. 2022 Dec;35(25):5431-5437. doi: 10.1080/14767058.2021.1882980. Epub 2021 Feb 9.
To investigate delivery indications for women with late preterm preeclampsia and evaluate whether disease characteristics at presentation are predictive of delivery indication.
We conducted a retrospective case-control study at the Mercy Hospital for Women (a tertiary hospital in Melbourne, Australia). Indication for delivery was assessed among women presenting with preeclampsia between 30 and 36 weeks' gestation. Baseline maternal and disease characteristics, preeclampsia features at delivery and postnatal outcomes were compared between patients delivering for maternal, fetal, or for both maternal and fetal indications.
173 women were diagnosed with preeclampsia between 30 and 36 weeks' gestation. Maternal baseline characteristics were similar between the groups. We found that 55.5% of women were delivered on maternal grounds compared to 27.2% requiring delivery for fetal indications; and 17.3% for both maternal and fetal indications ( < .0001). At diagnosis, intrauterine growth restriction and abnormal Dopplers increased the risk of requiring delivery for fetal indications by 3.5 times and 2.4 times respectively.
Women presenting with late preterm preeclampsia primarily required delivery for maternal disease progression rather than fetal compromise.
探讨患有晚期早产儿子痫前期的女性的分娩指征,并评估其发病时的疾病特征是否可预测分娩指征。
我们在澳大利亚墨尔本 Mercy 医院(一家三级医院)进行了一项回顾性病例对照研究。在妊娠 30 至 36 周出现子痫前期的女性中评估分娩指征。比较了因母体、胎儿或母体和胎儿指征而分娩的患者之间的基线母体和疾病特征、分娩时子痫前期特征和产后结局。
在妊娠 30 至 36 周期间,诊断出 173 例子痫前期患者。组间母体基线特征相似。我们发现,55.5%的女性因母体疾病进展而分娩,而需要因胎儿指征而分娩的比例为 27.2%;因母体和胎儿指征而分娩的比例为 17.3%( < 0.0001)。在诊断时,宫内生长受限和异常多普勒超声使因胎儿指征而需要分娩的风险分别增加了 3.5 倍和 2.4 倍。
患有晚期早产儿子痫前期的女性主要因母体疾病进展而需要分娩,而不是胎儿窘迫。