正电子发射断层扫描和磁共振成像在人类神经退行性疾病中枢神经系统药物评估中的作用。
Contributions of PET and MRI imaging in the evaluation of CNS drugs in human neurodegenerative diseases.
机构信息
Inserm, UPS, ToNIC, Nuclear Medicine Department, Toulouse NeuroImaging Center, University Hospital of Toulouse France, Université de Toulouse, 31000 Toulouse, France.
CNRS, CRMBM, Aix-Marseille University, 13385 Marseille, France; CEMEREM, AP-HM, University Hospital Timone, 13385 Marseille, France.
出版信息
Therapie. 2021 Mar-Apr;76(2):121-126. doi: 10.1016/j.therap.2020.12.008. Epub 2020 Dec 5.
This manuscript reviews the contributions of the neuroimaging methods including PET, conventional and advanced MRI methods to monitor the effect of new disease modifying drugs in neurodegenerative diseases. It now seems obvious that in many pathologies these two techniques are more and more complementary.
本文综述了神经影像学方法（包括 PET、常规和先进的 MRI 方法）在监测神经退行性疾病新型疾病修饰药物效果方面的贡献。现在看来，在许多病理情况下，这两种技术越来越具有互补性。
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