Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, China.
Department of Mini-invasive Spinal Surgery, Third Hospital of Henan Province, Zhengzhou, China.
Orthop Surg. 2021 Apr;13(2):641-650. doi: 10.1111/os.12925. Epub 2021 Feb 9.
To introduce a new surgery, percutaneous endoscopic unilateral laminotomy and bilateral decompression (Endo-ULBD) using visual trepan, and investigate its efficacy and safety in elderly patients with lumbar spinal stenosis. In our retrospective study, a total of 69 patients were enrolled between March 2018 and September 2018; 31 patients were treated with Endo-ULBD and 38 patients were treated with posterior lumbar interbody fusion surgery (PLIF). The operation time, intraoperative blood loss, and hospitalization duration were compared between the two groups. A visual analog scale (VAS) was used to evaluate the degree of pain. The Oswestry Disability Index (ODI) and European Quality of Life-5 Dimensions (EQ-5D) were used to evaluate lumbar function and quality of life, respectively. Lumbar X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) were performed postoperatively at different time points. MacNab's outcome assessment and perioperative complications were also documented. The surgeon completed all surgeries successfully, and all 69 patients were followed up. The operative time of the Endo-ULBD group was 60.68 ± 0.47 min, while that of the PLIF group was 120.23 ± 10.24 min. The operative time of the Endo-ULBD group was shorter than that of the PLIF group, and the difference was statistically significant (P < 0.001). The volume of intraoperative blood loss was 47.25 ± 0.43 mL in the Endo-ULBD group and 256.90 ± 20.83 mL in the PILF group (P < 0.001). The length of hospital stay in the Endo-ULBD group was 5.12 ± 1.60 days and that in the PILF group was 10.54 ± 1.82 days (P < 0.001). The VAS scores at postoperative 1 day, 3 months, 6 months, final follow-up (Endo-ULBD: 6.58 ± 0.65, 4.55 ± 0.54, 2.78 ± 0.24, 1.31 ± 0.78; PLIF: 7.19 ± 1.14, 4.80 ± 0.13, 2.71 ± 0.83, 1.29 ± 0.56) were significantly improved compared with those before surgery (Endo-ULBD: 8.63 ± 0.37; PLIF: 8.31 ± 1.34). The ODI and EQ-5D scores of lumbar function and quality of life at each time point after surgery (Endo-ULBD ODI: 30.29% ± 0.47%, 23.35% ± 0.95%, 19.45% ± 0.81%, 10.84% ± 0.36%; EQ-5D: 0.38 ± 0.15, 0.45 ± 0.17, 0.63 ± 0.14, 0.71 ± 0.20; PLIF ODI: 33.56% ± 1.58%, 25.69% ± 2.69%, 20.01% ± 1.49%, 10.72% ± 0.29%; EQ-5D: 0.33 ± 0.03, 0.39 ± 0.05, 0.62 ± 0.07, 0.72 ± 0.10) were significantly improved compared with those before surgery (Endo-ULBD: 44.56 ± 1.32, 0.33 ± 0.07; PLIF: 43.79 ± 1.91, 0.31 ± 0.09, respectively), with statistically significant differences (P < 0.05); however, there was no significant difference between the two groups at the last follow-up (P > 0.05). At the last follow-up, the excellent and good efficacy rate was 90.3% (28/31) in the Endo-ULBD group and 89.4% (34/38) in the PILF group (χ = 0.089, P = 0.993). No mortality, irreversible nerve injury, or even paralysis occurred in either group. Endo-ULBD for lumbar spinal stenosis has the advantages of less trauma, a shortened operation time, and rapid recovery and is an effective alternative for the treatment of lumbar spinal stenosis. Strict surgical indications, reasonable surgical plans, and experienced surgeons are important factors to ensure safety and satisfactory postoperative efficacy.
为了引入一种新的手术方法,即经皮内镜单侧椎板切除术和双侧减压术(Endo-ULBD)联合视觉环锯,并研究其在老年腰椎管狭窄症患者中的疗效和安全性。在我们的回顾性研究中,共纳入了 2018 年 3 月至 2018 年 9 月期间的 69 名患者;其中 31 名患者接受了 Endo-ULBD 治疗,38 名患者接受了后路腰椎体间融合术(PLIF)治疗。比较两组的手术时间、术中出血量和住院时间。使用视觉模拟量表(VAS)评估疼痛程度。使用 Oswestry 功能障碍指数(ODI)和欧洲生活质量 5 维度(EQ-5D)分别评估腰椎功能和生活质量。术后不同时间点行腰椎 X 线、计算机断层扫描(CT)和磁共振成像(MRI)检查。还记录了 MacNab 疗效评估和围手术期并发症。所有手术均由同一位外科医生完成,所有 69 名患者均获得随访。Endo-ULBD 组的手术时间为 60.68±0.47min,PLIF 组为 120.23±10.24min。Endo-ULBD 组的手术时间短于 PLIF 组,差异有统计学意义(P<0.001)。Endo-ULBD 组术中出血量为 47.25±0.43ml,PLIF 组为 256.90±20.83ml(P<0.001)。Endo-ULBD 组的住院时间为 5.12±1.60 天,PLIF 组为 10.54±1.82 天(P<0.001)。术后 1 天、3 个月、6 个月和最终随访时(Endo-ULBD:6.58±0.65、4.55±0.54、2.78±0.24、1.31±0.78;PLIF:7.19±1.14、4.80±0.13、2.71±0.83、1.29±0.56)的 VAS 评分均明显低于术前(Endo-ULBD:8.63±0.37;PLIF:8.31±1.34)。术后各时间点的 ODI 和 EQ-5D 评分(Endo-ULBD ODI:30.29%±0.47%、23.35%±0.95%、19.45%±0.81%、10.84%±0.36%;EQ-5D:0.38±0.15、0.45±0.17、0.63±0.14、0.71±0.20)明显优于术前(Endo-ULBD:44.56±1.32、0.33±0.07;PLIF:43.79±1.91、0.31±0.09),差异有统计学意义(P<0.05);但末次随访时两组差异无统计学意义(P>0.05)。末次随访时,Endo-ULBD 组优良率为 90.3%(28/31),PLIF 组为 89.4%(34/38)(χ=0.089,P=0.993)。两组均无死亡、不可逆性神经损伤,甚至瘫痪发生。经皮内镜单侧椎板切除术和双侧减压术治疗腰椎管狭窄症具有创伤小、手术时间短、恢复快的优点,是治疗腰椎管狭窄症的有效方法。严格的手术适应证、合理的手术计划和经验丰富的外科医生是保证手术安全和疗效满意的重要因素。