Department of Medicine, Hospital Pulau Pinang, Pulau Pinang, Malaysia.
Diagnostic Laboratory Services Department, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.
Saudi J Kidney Dis Transpl. 2020 Nov-Dec;31(6):1403-1406. doi: 10.4103/1319-2442.308356.
Anticoagulant-related nephropathy (ARN) is a recently described disease entity which is an underdiagnosed complication of anticoagulation. Despite widespread usage of anticoagulants, ARN is not commonly reported. We report a case of a 64-year old man with biopsy-proven ARN who presented with over anticoagulation and acute chronic kidney injury while on warfarin therapy for his left lower limb deep-vein thrombosis. Various investigations were performed and renal biopsy confirmed the diagnosis of anticoagulant-related nephropathy.
抗凝相关肾病(ARN)是一种新近描述的疾病实体,是抗凝治疗中一种未被充分诊断的并发症。尽管抗凝剂广泛应用,但 ARN 并不常见。我们报告了一例 64 岁男性患者,因左下肢深静脉血栓形成接受华法林治疗时发生抗凝过度和急性慢性肾损伤,经活检证实为 ARN。进行了各种检查,肾活检证实了抗凝相关肾病的诊断。