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孟加拉国农民患未确诊的慢性肾脏病和β-地中海贫血症时并发败血性类鼻疽病。

Septicemic melioidosis complicating undiagnosed chronic kidney disease and beta-thalassemia minor in a Bangladeshi farmer.

机构信息

Department of Nephrology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, Bangladesh.

出版信息

Saudi J Kidney Dis Transpl. 2020 Nov-Dec;31(6):1411-1414. doi: 10.4103/1319-2442.308358.

Abstract

Melioidosis is an emerging infectious disease in many countries including Bangladesh. Patients with diabetes mellitus are at increased risk for infection by Burkholderia pseudomallei, the causative agent for melioidosis. Here, we report an autochthonous case of septicemic melioidosis occurring in a middle-aged non-diabetic Bangladeshi farmer who presented with prolonged pyrexia and splenomegaly. Diagnostic workup revealed splenic micro-abscesses, previously undetected chronic kidney disease (CKD) and beta-thalassemia minor. This case stresses the importance of searching for less common risk factors for melioidosis such as CKD and hemolytic anemia.

摘要

类鼻疽是包括孟加拉国在内的许多国家出现的一种新发传染病。糖尿病患者感染类鼻疽伯克霍尔德菌(导致类鼻疽的病原体)的风险增加。在这里,我们报告了一例发生在中年非糖尿病孟加拉国农民身上的血源性类鼻疽本地感染病例,该患者表现为长期发热和脾肿大。诊断工作显示脾微脓肿、先前未发现的慢性肾脏病(CKD)和β-地中海贫血。本病例强调了寻找类鼻疽不太常见的危险因素(如 CKD 和溶血性贫血)的重要性。

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