Palmer J E, Whitlock R H, Benson C E
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
J Am Vet Med Assoc. 1988 Feb 1;192(3):343-5.
Equine ehrlichial colitis was experimentally induced in 18 ponies, using Ehrlichia risticii-infected blood. Four ponies (group 1) were treated with oxytetracycline (6.6 mg/kg of body weight, IV, q 12 h), beginning 14 hours before inoculation and continuing for 5 days after inoculation. Four additional ponies (group 2) were treated similarly for 10 days after inoculation. The remaining 10 ponies were used as nontreated, infected controls. Clinical disease was delayed in 3 group-1 ponies and in 4 group-2 ponies. Protective immunity developed in the remaining pony that did not develop clinical disease and in 1 group-1 pony and 2 group-2 ponies that developed mild, transient clinical signs.
