Orozco-Sevilla Vicente, Coselli Joseph S
Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Department of Cardiovascular Surgery, Texas Heart Institute, Houston, TX, USA.
J Cardiovasc Surg (Torino). 2021 Aug;62(4):302-315. doi: 10.23736/S0021-9509.21.11806-3. Epub 2021 Feb 10.
Most operations for dissection of the thoracoabdominal aorta take place in the chronic phase of the disease, because the acutely dissected distal aorta is almost always initially treated non-surgically with aggressive pharmacological anti-impulse therapy. Identifying patients who are no longer responding to medical treatment is the first step in preventing further disease progression and rupture. Symptomatic aneurysms should be promptly repaired. Asymptomatic patients are followed until significant aortic dilation occurs and reaches a threshold of intervention: current guidelines endorse repair once a diameter of 5.5 cm is reached. In patients with heritable thoracic aortic disease (such as Marfan Syndrome), the threshold of intervention is often lowered. Aortic replacement typically centers on the dilatated segment. For all extents of repair, we use passive mild hypothermia, sequential aortic cross-clamping, aggressive reimplantation of intercostal and lumbar arteries, and cold renal perfusion whenever possible. For Crawford extents I and II thoracoabdominal aneurysm repair, we routinely use cerebrospinal fluid drainage, left heart bypass, and selective visceral perfusion. A four-branched graft approach to thoracoabdominal aortic aneurysm repair is frequently used in patients with chronic aortic dissection; this approach facilitates visceral artery perfusion during repair, expedites the distal anastomosis, and prevents subsequent visceral patch aneurysms. Lifelong imaging surveillance is necessary, because the distal aorta often continues to expand; residual aortic dissection commonly remains after repair and may necessitate further repair.
大多数胸腹主动脉夹层手术在疾病的慢性期进行,因为急性夹层的远端主动脉几乎总是首先采用积极的药物抗搏动治疗进行非手术治疗。识别对药物治疗不再有反应的患者是预防疾病进一步进展和破裂的第一步。有症状的动脉瘤应立即修复。无症状患者进行随访,直到出现明显的主动脉扩张并达到干预阈值:目前的指南支持一旦直径达到5.5厘米就进行修复。对于遗传性胸主动脉疾病(如马凡综合征)患者,干预阈值通常会降低。主动脉置换通常以扩张段为中心。对于所有修复范围,我们尽可能采用被动轻度低温、序贯主动脉交叉钳夹、积极再植肋间动脉和腰动脉以及冷肾灌注。对于克劳福德I型和II型胸腹主动脉瘤修复,我们常规使用脑脊液引流、左心转流和选择性内脏灌注。四分支移植物方法常用于慢性主动脉夹层患者的胸腹主动脉瘤修复;这种方法便于修复过程中的内脏动脉灌注,加快远端吻合,并防止随后的内脏补片动脉瘤。终身影像学监测是必要的,因为远端主动脉通常会继续扩张;修复后通常会残留主动脉夹层,可能需要进一步修复。