Kopcha M
Department of Food Animal Medicine and Surgery, Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
J Am Vet Med Assoc. 1988 Mar 15;192(6):783-4.
On the basis of chronic weight loss, bilateral asymmetric abdominal distention, ballottement of a large abomasum, hypochloremic metabolic alkalosis, and high rumen chloride concentration, an adult Suffolk ewe was diagnosed as having an abomasal emptying defect. In this ewe, and in 4 of 7 other sheep diagnosed as having abomasal emptying defects, aspartate transaminase and sorbitol dehydrogenase activities were high, and histopathologic evidence of hepatic congestion and ischemia was found. It was theorized that increased intra-abdominal pressure from abomasal distention may be the cause of the hepatic abnormalities. These changes have not been previously associated with ovine abomasal emptying defect, the pathogenic mechanism of which remains unclear.
基于慢性体重减轻、双侧不对称腹部膨胀、大真胃冲击触诊、低氯性代谢性碱中毒以及瘤胃氯浓度升高，一只成年萨福克母羊被诊断为真胃排空障碍。在这只母羊以及另外7只被诊断为真胃排空障碍的绵羊中的4只中，天冬氨酸转氨酶和山梨醇脱氢酶活性升高，并且发现了肝脏充血和缺血的组织病理学证据。据推测，真胃扩张导致的腹内压升高可能是肝脏异常的原因。这些变化以前未与绵羊真胃排空障碍相关联，其致病机制仍不清楚。
