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寻找鼻甲肥大儿童减充血试验的截断值。

Looking for a cutoff value for the decongestant test in children suffering with turbinate hypertrophy.

机构信息

Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS) Rhinology Study Group, Paris, France.

Service of Otolaryngology, Rhinology Section, Hospital Complex of Santiago de Compostela, s/n. 15706, Santiago de Compostela, Spain.

出版信息

Eur Arch Otorhinolaryngol. 2021 Oct;278(10):3821-3826. doi: 10.1007/s00405-021-06657-0. Epub 2021 Feb 10.

Abstract

OBJECTIVE

The main causes for objectively confirmed chronic impaired nasal breathing in children are adenoid and turbinate hypertrophy. Turbinate hypertrophy may be addressed by turbinate surgery. However, specialized guidelines include no specific indications for pediatric patients. The decongestant test consists of simulating the effect of turbinate surgery by means of a nasal decongestant. This project, developed by the YO-IFOS rhinology group, aims to establish a cutoff value for the nasal decongestant test with rhinomanometry to select children for turbinate surgery.

METHODS

Children between 4 and 15 years of age were included. Cases were consecutively selected from children affected by turbinate hypertrophy undergoing turbinate radiofrequency ablation with or without adenoidectomy. Controls were consecutively selected from a sample of healthy children. All the subjects were examined with anterior active rhinomanometry with and without nasal decongestant.

RESULTS

Sample included 72 cases and 24 healthy controls. There was a statistically significant difference in the improvement with the decongestant between cases (57.91%) and controls (15.67%). The ROC curve revealed an area under the curve of 0.97. The highest amount of correctly classified individuals (93.44%) corresponded to the cutoff value of 31.66%. However, the value with the highest specificity and highest Youden's index was the 38.88% improvement in nasal resistance with nasal decongestant.

CONCLUSIONS

In conclusion, a preliminary cutoff value for the decongestant test used with rhinomanometry in children has been established. This test could help identify children for turbinate surgery.

摘要

目的

儿童经客观证实的慢性鼻塞的主要原因是腺样体和鼻甲肥大。鼻甲肥大可以通过鼻甲手术来解决。然而,专业指南并未为儿科患者提供具体的适应证。减充血剂测试通过使用鼻减充血剂模拟鼻甲手术的效果。这个由 YO-IFOS 鼻科学组开发的项目旨在建立一个鼻阻力计鼻减充血剂测试的截断值,以便为鼻甲手术选择儿童。

方法

纳入年龄在 4 至 15 岁之间的儿童。病例组为接受鼻甲射频消融术联合或不联合腺样体切除术的鼻甲肥大患儿,连续选择。对照组为健康儿童的样本,连续选择。所有受试者均接受前鼻主动测压法和鼻减充血剂检查。

结果

样本包括 72 例病例和 24 例健康对照。病例组(57.91%)与对照组(15.67%)在减充血剂后的改善程度存在统计学差异。ROC 曲线显示曲线下面积为 0.97。正确分类个体的比例最高(93.44%)对应于截断值为 31.66%。然而,具有最高特异性和最高 Youden 指数的是鼻阻力经鼻减充血剂改善 38.88%。

结论

总之,已经为儿童使用鼻阻力计进行鼻减充血剂测试建立了一个初步的截断值。该测试有助于识别需要鼻甲手术的儿童。

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