Steinacker J M, Spittelmeister W
Abteilung für Angewandte Physiologie, Universität Ulm, Federal Republic of Germany.
J Appl Physiol (1985). 1988 Jan;64(1):21-5. doi: 10.1152/jappl.1988.64.1.21.
Transcutaneous PO2 was measured using a transcutaneous PO2 electrode heated to 45 degrees C on the forearm of 19 healthy volunteers. Cutaneous blood flow (CBF) was estimated indirectly from the heating power of the electrode (HP) and with an 8-MHz bidirectional ultrasonic probe by Doppler shift in a fingertip at 45 degrees C (DF). Blood flow was regulated by an upper arm cuff. Mean transcutaneous PO2 during air respiration was 86.0 +/- 6.2 Torr, and the correlation to arterial PO2 (Pao2) was 0.96 at normal blood flow. The arterial inflow was intermittently reduced in 10-15% stages of effective perfusion pressure (Peff). There was a hyperbolic decrease in PO2 when CBF was restricted in stages. A linear dependence between Peff, HP, and DF was found, which means that there is no autoregulation in the capillary bed at 45 degrees C. Transcutaneous PO2 can be also taken as an indication of CBF. The transcutaneous index, transcutaneous PO2/Pao2, is helpful for estimating local O2 availability.
使用加热至45摄氏度的经皮氧分压电极，在19名健康志愿者的前臂测量经皮氧分压。通过电极加热功率（HP）以及在45摄氏度时利用指尖处8兆赫双向超声探头的多普勒频移（DF）间接估计皮肤血流量（CBF）。血流量由上臂袖带调节。在空气呼吸期间，平均经皮氧分压为86.0±6.2托，在正常血流情况下与动脉氧分压（Pao2）的相关性为0.96。在有效灌注压（Peff）的10 - 15%阶段间歇性减少动脉流入。当按阶段限制CBF时，氧分压呈双曲线下降。发现Peff、HP和DF之间存在线性关系，这意味着在45摄氏度时毛细血管床不存在自身调节。经皮氧分压也可作为CBF的指标。经皮指数，即经皮氧分压/Pao2，有助于估计局部氧的可利用性。
