Dobner Stephan, Gräni Christoph, Hugi-Mayr Beate, Mihalj Maks, Rhyner Daniel, Wieser Monika, Martinelli Michele, Hunziker Lukas, Reineke David
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
ESC Heart Fail. 2021 Apr;8(2):1631-1636. doi: 10.1002/ehf2.13244. Epub 2021 Feb 10.
Over the past decade, left ventricular assist device (VAD) therapy has become more prevalent and increasingly safe. Severe complications, such as VAD pump thrombosis and outflow graft obstruction, are rare, yet still associated with high morbidity and mortality. Clinical presentation, VAD alarm and log files, laboratory analysis, and non-invasive cardiac imaging are crucial for establishing the correct diagnosis and determining clinical management. Early intervention is critical to prevent adverse cardiac remodelling or VAD pump failure.
在过去十年中，左心室辅助装置（VAD）治疗变得更加普遍且安全性日益提高。严重并发症，如VAD泵血栓形成和流出道移植物梗阻，虽较为罕见，但仍与高发病率和死亡率相关。临床表现、VAD警报和日志文件、实验室分析以及无创心脏成像对于确立正确诊断和确定临床管理至关重要。早期干预对于预防不良心脏重塑或VAD泵衰竭至关重要。
