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秘鲁利马一家国立医院住院患者抗生素使用情况。

Use of antibiotics in inpatients from a national hospital in Lima, Peru.

机构信息

Servicio de Enfermedades Infecciosas y Tropicales, Hospital Nacional Dos de Mayo, Lima, Perú.

Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Perú.

出版信息

Rev Peru Med Exp Salud Publica. 2020 Oct-Dec;37(4):620-626. doi: 10.17843/rpmesp.2020.374.5073. Epub 2021 Feb 3.

DOI:10.17843/rpmesp.2020.374.5073
PMID:33566900
Abstract

OBJECTIVE

To determine the point prevalence and characteristics of antibiotic use in different hospitalization areas of the Hospital Nacional Dos de Mayo.

MATERIALS AND METHODS

We carried out a 3-week cross-sectional study with a census approach (using methodology from the World Health Organization) to determine the point prevalence of antibiotic use in inpatients from hospitalization areas, regardless of whether or not they were on an antibiotic regimen.

RESULTS

We identified 358 patients, with a mean age of 49 (± 25.3) years, predominantly adults (88%). Antibiotics were used in 51.7% of the hospitalized patients; only 57.3% of the prescriptions followed a regimen based on clinical practice guidelines for antibiotic treatment, while 28.5% did not follow any standardized recommendation. Therapies were empirical in 86.8% and directed in 13.2% of the cases.

CONCLUSIONS

Antibiotics were used in more than 50% of hospitalized patients. However, about one third of the prescriptions were not based on any clinical practice guidelines. Despite the existence of an antimicrobial control program in the hospital, appropriate antimicrobial use still needs to be optimized.

摘要

目的

确定 2 家 Mayo 国民医院不同住院科室抗生素使用的时点患病率和特征。

材料和方法

我们开展了一项横断面研究,采用整群抽样方法(采用世界卫生组织的方法),以确定住院患者的抗生素使用时点患病率,无论他们是否接受抗生素治疗方案。

结果

我们共确定了 358 名患者,平均年龄为 49(±25.3)岁,主要为成年人(88%)。51.7%的住院患者使用了抗生素;只有 57.3%的处方遵循了基于抗生素治疗临床实践指南的方案,而 28.5%的处方没有遵循任何标准化建议。86.8%的治疗方案为经验性治疗,13.2%为靶向治疗。

结论

超过 50%的住院患者使用了抗生素。然而,大约三分之一的处方没有依据任何临床实践指南。尽管医院存在抗菌药物管理计划,但仍需要优化适当的抗菌药物使用。

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