Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Rio de Janeiro, RJ, Brasil.
Mem Inst Oswaldo Cruz. 2021 Feb 3;115:e200521. doi: 10.1590/0074-02760200521. eCollection 2021.
Outbreaks of a vesiculopustular disease in dairy cattle and milkers have been frequently reported in Brazil since 1999 when the vaccinia virus strain Cantagalo was first isolated in the State of Rio de Janeiro. However, the genomic diversity of the viral isolates associated with these outbreaks is not well known, particularly in the southeastern states that represent the focal point of virus spread to other regions. Here, we report the genomic sequences and an analysis of the polymorphic site profiles and genotypic diversity of four clinical isolates of vaccinia virus strain Cantagalo collected from 1999 to 2006 in southeastern Brazil.
自 1999 年巴西里约热内卢州首次分离出坎塔加洛牛痘病毒株以来，巴西就频繁报道了奶牛和挤奶工中爆发的水疱脓疱病。然而，与这些疫情相关的病毒分离株的基因组多样性尚不清楚，特别是在东南部各州，这些州是病毒传播到其他地区的焦点。在这里，我们报告了从 1999 年到 2006 年在巴西东南部收集的四个临床坎塔加洛牛痘病毒株的基因组序列和多态性位点图谱以及基因型多样性分析。
