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老年白血病的治疗(作者译)

[Treatment of leukemia in the elderly (author's transl)].

作者信息

Höcker P

出版信息

Aktuelle Gerontol. 1979 Jan;9(1):27-33.

PMID:33567
Abstract

The treatment of elderly patients, who suffer from leukemia must not be standardized. Impaired bone marrow function, cardiovascular disease and other organopathias require an individually adapted therapy. The aim of treatment should be a good quality of life and not a remission at any price. Aggressive therapy in cases of acute leukemia with little progress should be avoided in favour of symptomatic treatment. CLL are treated in the progressive state of disease. Haemolytic anaemia and recurrent infections may complicate the course of CLL. CML is not a disease of old age but when it occurs intermittent therapy with cautious dosage is preferable to a continuous therapy.

摘要

老年白血病患者的治疗不能标准化。骨髓功能受损、心血管疾病和其他器官病变需要个体化的适应性治疗。治疗的目标应该是良好的生活质量,而不是不惜一切代价实现缓解。对于进展甚微的急性白血病病例,应避免激进治疗,而采用对症治疗。慢性淋巴细胞白血病(CLL)在疾病进展期进行治疗。溶血性贫血和反复感染可能使CLL的病程复杂化。慢性粒细胞白血病(CML)并非老年疾病,但当它发生时,间歇治疗且谨慎用药比持续治疗更可取。

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