Diagnostic Imaging Service, U-Vet Werribee Animal Hospital, Werribee, Victoria, Australia.
Vet Radiol Ultrasound. 2021 Jul;62(4):437-444. doi: 10.1111/vru.12957. Epub 2021 Feb 10.
Contrast-enhanced computed tomography (CT) is increasingly being used as a standard diagnostic test for dogs with suspected abdominal pathology. The iodinated contrast dose is commonly calculated based on linear increases in total body weight. However, body fat is not metabolically active and contributes little to dispersing or diluting the contrast medium in the blood. The aim of this retrospective single-center analytic study was to investigate the possible correlation between abdominal organ and vessel enhancement, and abdominal fat percentage in dogs. We hypothesized that, when dosing intravenous iodinated contrast according to total body weight, there would be a positive association between the degree of contrast enhancement of selected organs and vessels with increasing abdominal fat percentage. Vascular and parenchymal attenuation data were collected from 62 multiphasic abdominal CECT scans performed on dogs over a 5-year period at U-Vet Werribee Animal Hospital between February 2014 and February 2019. Findings based on a linear regression model showed a positive association of aorta (P = .005), liver (P = .045), and portal vein (P = .001) enhancement to abdominal fat percentage during the portal venous phase. Authors recommend that other body size parameters, such as lean body weight, should be considered when calculating iodine dose for abdominal contrast-enhanced CT in dogs.
对比增强计算机断层扫描（CT）越来越多地被用作疑似腹部病变犬的标准诊断测试。碘造影剂剂量通常根据体质量的线性增加来计算。然而，体脂没有代谢活性，对血液中造影剂的分散或稀释作用贡献不大。本回顾性单中心分析研究的目的是探讨犬腹部器官和血管增强与腹部脂肪百分比之间的可能相关性。我们假设，当根据体质量静脉内给予碘造影剂时，随着腹部脂肪百分比的增加，选定的器官和血管的造影增强程度与腹部脂肪百分比之间存在正相关。在 2014 年 2 月至 2019 年 2 月期间，U-Vet Werribee 动物医院在 5 年期间对 62 例多期腹部 CECT 扫描进行了血管和实质衰减数据采集。基于线性回归模型的结果显示，门静脉期主动脉（P =.005）、肝脏（P =.045）和门静脉（P =.001）增强与腹部脂肪百分比呈正相关。作者建议，在计算犬腹部增强 CT 的碘剂量时，应考虑其他身体尺寸参数，如瘦体重。
