Alliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, 1067University of South Australia, Adelaide, Australia.
Central and Northern Adelaide Renal and Transplantation Service Clinical Research Group, 1062Royal Adelaide Hospital, Australia.
Perit Dial Int. 2021 Sep;41(5):502-508. doi: 10.1177/0896860821992243. Epub 2021 Feb 11.
Fatigue is a frequent and debilitating symptom for people with end-stage kidney disease (ESKD) receiving dialysis. Ecological momentary assessment (EMA) allows real-time data capture of day-to-day and diurnal variations. EMA has been used to study haemodialysis-related fatigue but not in people receiving peritoneal dialysis who are unique in their physical, environmental and logistical characteristics. The aim of this study is to explore the real-time associations between fatigue and mood (EMA mobile application) and objective physical activity levels (accelerometry) in people with EKSD receiving peritoneal dialysis.
A 7-day intensive longitudinal study will be conducted. People receiving peritoneal dialysis within South Australia will be invited to participate. Five times throughout the day, participants will be prompted to answer 18 questions relating to fatigue (Visual Analogue Scale to Evaluate Fatigue Severity) and a single question for mood (Visual Analogue Mood Scale). Participants will continuously wear a GENEActiv accelerometer to capture physical activity levels during the 7-day period. At the completion of the data collection, participants will answer questions to evaluate the feasibility and acceptability of using EMA.
This study will be the first to explore the real-time relationships between fatigue, mood and physical activity in people with ESKD receiving peritoneal dialysis. Understanding the fluctuations people experience and the relationships between mood and physical activity and fatigue will inform clinical management and well-being intervention development.
对于接受透析治疗的终末期肾病(ESKD)患者来说,疲劳是一种常见且虚弱的症状。生态瞬时评估(EMA)允许实时捕获日常和昼夜变化的数据。EMA 已被用于研究血液透析相关性疲劳,但尚未在接受腹膜透析的患者中使用,这些患者在身体、环境和后勤方面具有独特的特征。本研究旨在探索腹膜透析 ESKD 患者的疲劳和情绪(EMA 移动应用程序)与客观体力活动水平(加速度计)之间的实时关联。
将进行为期 7 天的强化纵向研究。将邀请南澳大利亚州内接受腹膜透析的患者参加。每天五次,参与者将被提示回答 18 个与疲劳相关的问题(评估疲劳严重程度的视觉模拟量表)和一个关于情绪的单一问题(视觉模拟情绪量表)。参与者将在 7 天内连续佩戴 GENEActiv 加速度计以记录体力活动水平。在数据收集完成后,参与者将回答问题,以评估使用 EMA 的可行性和可接受性。
这将是第一项探索接受腹膜透析的 ESKD 患者疲劳、情绪和体力活动之间实时关系的研究。了解人们所经历的波动以及情绪和体力活动与疲劳之间的关系,将为临床管理和幸福感干预措施的发展提供信息。