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[类风湿关节炎的基础治疗]

[Basic therapy of rheumatoid arthritis].

出版信息

Z Gesamte Inn Med. 1977 Jul 15;32(14):328-33.

PMID:335680
Abstract

Apart from the conventional treatment of the rheumatoid arthritis with steroidal and non-steroidal antirheumatic remedies, physiotherapy and balneotherapy as well as orthopaedic and surgical measures the basis therapy is an important factor. It has no or only slight analgetic effect, but shall inhibit the immunological processes in the pathogenesis of the rheumatoid arthritis. To the basis therapy belong the antimalarial remedies, the gold salts, the cytostatic remedies as immunosuppressive drugs and the D-penicillamine. Their possible and different modes of action are described, their clinical applications are explained and it is referred to their side-effects and contraindications. In these cases also the value of the individual preparations in the complex plan of treatment of rheumatoid arthritis are evaluated.

摘要

除了使用甾体和非甾体抗风湿药物、物理治疗、温泉疗法以及矫形和外科措施对类风湿性关节炎进行常规治疗外,基础治疗也是一个重要因素。它没有或只有轻微的镇痛作用,但应抑制类风湿性关节炎发病机制中的免疫过程。基础治疗包括抗疟药物、金盐、作为免疫抑制药物的细胞毒性药物和D-青霉胺。描述了它们可能的不同作用方式,解释了它们的临床应用,并提及了它们的副作用和禁忌症。在这些情况下,还评估了个别制剂在类风湿性关节炎综合治疗方案中的价值。

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