越南顺化市2型糖尿病患者的抑郁症：患病率及相关因素
Depression Among Patients with Type 2 Diabetes Mellitus: Prevalence and Associated Factors in Hue City, Vietnam.
作者信息
Tran Nhu Minh Hang, Nguyen Quang Ngoc Linh, Vo Thi Han, Le Tran Tuan Anh, Ngo Ngoc Ha
机构信息
Department of Psychiatry, Hue University of Medicine and Pharmacy, Hue University, Hue, Thua Thien Hue, Vietnam.
Preventive Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Thua Thien Hue, Vietnam.
出版信息
Diabetes Metab Syndr Obes. 2021 Feb 4;14:505-513. doi: 10.2147/DMSO.S289988. eCollection 2021.
BACKGROUND AND AIMS
Depression is common in people with type 2 diabetes mellitus. The association of depression and diabetes has negative effects on patients. This study investigated the prevalence of depression in individuals with type 2 diabetes mellitus and examined the social, psychological and clinical factors associated with depression.
PATIENTS AND METHODS
The study included 216 inpatients with type 2 diabetes mellitus at the Department of Endocrinology and Neurology, Hue Central Hospital and the Department of General Internal Medicine, Hue University Hospital. This descriptive cross-sectional study evaluated depression using the Patient Health Questionnaire-9 (PHQ-9). Data were collected on patients' socio-demographic factors such as sex, age, marital and economic status, level of education and clinical factors including duration of type 2 diabetes mellitus, fasting blood glucose, HbA1C, comorbidities or complications as well as health behavior including alcohol consumption, smoking and physical activities. Logistic regression was used to analyze the factors associated with depression in patients with type 2 diabetes mellitus.
RESULTS
23.2% of the patients had depression. The rates of severe, moderate and mild depression were 0.5, 0.9 and 21.8%, respectively. Multivariate logistic regression analysis indicated several factors associated with depression in participants, including age under 60 years, poor economic status, unstable or part-time work, having stress during the past year, without/poor treatment adherence to type 2 diabetes mellitus, and engaging in heavy physical activity or physical activity less than three days per week.
CONCLUSION
The prevalence of depression among patients with type 2 diabetes mellitus is high. Endocrinologists should be made aware of the increased risk of depression in this patient population and screening individuals for relevant risk factors is highly recommended.
背景与目的
抑郁症在2型糖尿病患者中很常见。抑郁症与糖尿病的关联对患者有负面影响。本研究调查了2型糖尿病患者中抑郁症的患病率，并探讨了与抑郁症相关的社会、心理和临床因素。
患者与方法
本研究纳入了顺化中央医院内分泌科与神经科以及顺化大学医院普通内科的216例2型糖尿病住院患者。这项描述性横断面研究使用患者健康问卷-9（PHQ-9）评估抑郁症。收集了患者的社会人口统计学因素数据，如性别、年龄、婚姻和经济状况、教育程度，以及临床因素，包括2型糖尿病病程、空腹血糖、糖化血红蛋白、合并症或并发症，还有健康行为，包括饮酒、吸烟和体育活动。采用逻辑回归分析2型糖尿病患者中与抑郁症相关的因素。
结果
23.2%的患者患有抑郁症。重度、中度和轻度抑郁症的发生率分别为0.5%、0.9%和21.8%。多因素逻辑回归分析表明，参与者中与抑郁症相关的几个因素包括60岁以下、经济状况差、工作不稳定或兼职、过去一年有压力、未/未良好坚持2型糖尿病治疗，以及每周进行剧烈体育活动或体育活动少于三天。
结论
2型糖尿病患者中抑郁症的患病率很高。内分泌科医生应意识到该患者群体患抑郁症的风险增加，强烈建议对个体进行相关危险因素筛查。
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