Le Minh Hoang, Le Ngoc Diem, Le Thi Thuy Nhu, Nguyen Minh Cuong, Tran Van De
Faculty of Traditional Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam.
General Hospital of O Mon District, Can Tho, Vietnam.
J Diabetes Res. 2025 May 29;2025:8885209. doi: 10.1155/jdr/8885209. eCollection 2025.
Previous research has focused largely on sociodemographic, clinical, and medication-use characteristics, overlooking the critical role psychosocial factors may play in influencing the medication-related burden among patients with Type 2 diabetes mellitus. The aim of this study was to explore the psychosocial factors associated with medication burden among patients with Type 2 diabetes mellitus. A cross-sectional study was performed on 261 patients with Type 2 diabetes from four community health stations in Can Tho, Vietnam. Linear regression models were used to identify demographic and health factors, as well as psychosocial factors, including medication self-efficacy, medication social support, satisfaction with medication treatments, depression, and medication beliefs that are related to medication burden. The presence of dyslipidemia ( = 0.15, = 0.002) and depression ( = 0.21, < 0.001) and a stronger belief in the necessity of medication ( = 0.41, < 0.001) were significantly associated with increased medication-related burden. Conversely, higher education ( = -0.16, = 0.002), a greater number of family members ( = -0.25, < 0.001), and higher medication self-efficacy ( = -0.21, < 0.001) were significantly associated with a reduction in medication-related burden. Psychosocial factors were found to be associated with medication burden among patients with Type 2 diabetes. These findings highlight the importance of psychosocial factors in managing medication burden. Future interventions should focus on these factors to reduce the medication burden and improve the quality of life for patients with Type 2 diabetes.
以往的研究主要集中在社会人口学、临床和用药特征方面，忽视了心理社会因素在影响2型糖尿病患者用药相关负担中可能发挥的关键作用。本研究的目的是探讨2型糖尿病患者中与用药负担相关的心理社会因素。对越南芹苴市四个社区卫生站的261名2型糖尿病患者进行了横断面研究。采用线性回归模型来确定人口统计学和健康因素，以及心理社会因素，包括用药自我效能感、用药社会支持、对药物治疗的满意度、抑郁和与用药负担相关的用药信念。血脂异常（β = 0.15，P = 0.002）、抑郁（β = 0.21，P < 0.001）以及对用药必要性的更强信念（β = 0.41，P < 0.001）与用药相关负担增加显著相关。相反，高等教育程度（β = -0.16，P = 0.002）、更多的家庭成员数量（β = -0.25，P < 0.001）和更高的用药自我效能感（β = -0.21，P < 0.001）与用药相关负担的减轻显著相关。研究发现心理社会因素与2型糖尿病患者的用药负担相关。这些发现凸显了心理社会因素在管理用药负担方面的重要性。未来的干预措施应关注这些因素，以减轻用药负担并改善2型糖尿病患者的生活质量。
