Bisai Milan Kumar, Gour Kritika, Das Tamal, Vanka Kumar, Sen Sakya S
Inorganic Chemistry and Catalysis Division, CSIR-National Chemical Laboratory, Dr Homi Bhabha Road, Pashan, Pune 411008, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India and Physical and Material Chemistry Division, CSIR-National Chemical Laboratory, Dr Homi Bhabha Road, Pashan, Pune 411008, India.
Dalton Trans. 2021 Feb 23;50(7):2354-2358. doi: 10.1039/d1dt00364j.
A selective and efficient route for the deoxygenative reduction of primary to tertiary amides to corresponding amines has been achieved with pinacolborane (HBpin) using simple and readily accessible 2,6-di-tert-butyl phenolate lithium·THF (1a) as a catalyst. Both experimental and DFT studies provide mechanistic insight.
使用简单且易于获得的2,6-二叔丁基苯酚锂·四氢呋喃（1a）作为催化剂，通过频哪醇硼烷（HBpin）实现了将伯酰胺脱氧还原为相应叔胺的选择性高效途径。实验和密度泛函理论（DFT）研究均提供了机理见解。
