Dept. of Chemistry, University of Hamburg, Martin Luther King Pl 6, 20146, Hamburg, Germany.
Angew Chem Int Ed Engl. 2021 Jul 12;60(29):16035-16043. doi: 10.1002/anie.202103550. Epub 2021 Jun 9.
Reductive transformations of easily available oxidized matter are at the heart of synthetic manipulation and chemical valorization. The applications of catalytic hydrofunctionalization benefit from the use of liquid reducing agents and operationally facile setups. Metal-catalyzed hydroborations provide a highly prolific platform for reductive valorizations of stable C=X electrophiles. Here, we report an especially facile, broad-scope reduction of various functions including carbonyls, carboxylates, pyridines, carbodiimides, and carbonates under very mild conditions with the inexpensive pre-catalyst Mn(hmds) . The reaction could be successfully applied to depolymerizations.
易得的氧化物质的还原转化是合成操作和化学增值的核心。催化氢官能化的应用得益于液体还原剂的使用和操作简单的设置。金属催化的硼氢化提供了一个高度丰富的平台，用于稳定的 C=X 亲电试剂的还原增值。在这里，我们报告了一种特别简单、广泛的还原方法，可以在非常温和的条件下，使用廉价的预催化剂 Mn(hmds) ，还原各种官能团，包括羰基、羧酸盐、吡啶、碳二亚胺和碳酸盐。该反应可以成功地应用于解聚。
