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多中心注册研究中经皮慢性完全闭塞冠状动脉介入治疗的辐射暴露:术者变异性和技术设置的影响。

Radiation Exposure for Percutaneous Interventions of Chronic Total Coronary Occlusions in a Multicenter Registry: The Influence of Operator Variability and Technical Set-up.

机构信息

Medizinische Klinik I, Klinikum Darmstadt GmbH, Grafenstrasse 9, D-64283 Darmstadt, Germany.

出版信息

J Invasive Cardiol. 2021 Mar;33(3):E146-E154. Epub 2021 Feb 11.

Abstract

AIMS

Radiation exposure is a limiting factor for percutaneous coronary interventions (PCI) of chronic total coronary occlusion (CTO) lesions. This study was designed to analyze changes in patient radiation dose for CTO-PCI and parameters associated with radiation dose.

METHODS AND RESULTS

We analyzed a cohort of 12,136 procedures performed by 23 operators between 2012 and 2017 from the European Registry of CTO-PCI. Radiation exposure was recorded as air kerma (AK) and dose area product (DAP). A dose rate index (DRI) was calculated as AK per fluoroscopy time to normalize for individual differences in fluoroscopy time. The lesion complexity increased from Japanese-CTO (J-CTO) score of 2.19 ± 1.44 to 2.46 ± 1.28, with an increase of retrograde procedures from 31.1% to 40.7%; still, procedural success improved from 87.7% to 92.1%. Fluoroscopy time remained similar, but AK decreased by 14.9%, from 2.35 Gy (interquartile range [IQR], 1.29-4.14 Gy) to 2.00 Gy (IQR, 1.08-3.45 Gy) and DAP decreased by 21.5%, from 130 Gy•cm² (IQR, 70-241 Gy•cm²) to 102 Gy•cm² (IQR, 58-184 Gy•cm²). Radiation exposure was determined by the lesion complexity (J-CTO score) and procedural complexity (antegrade or retrograde). DRI was determined by fluoroscopy frame rate and type of equipment used, but the major influence remained interoperator differences.

CONCLUSIONS

Radiation exposure decreased during the observation period despite an increase in lesion and procedural complexity. While many operators already achieved a goal of low radiation exposure, there were considerable interoperator differences in radiation management, indicating further potential for improvement.

摘要

目的

辐射暴露是经皮冠状动脉介入治疗(PCI)慢性完全闭塞(CTO)病变的限制因素。本研究旨在分析 CTO-PCI 患者的辐射剂量变化及与辐射剂量相关的参数。

方法和结果

我们分析了 2012 年至 2017 年期间来自欧洲 CTO-PCI 注册中心的 23 名术者进行的 12136 例手术。辐射暴露记录为空气比释动能(AK)和剂量面积乘积(DAP)。通过将 AK 除以透视时间来计算剂量率指数(DRI),以标准化透视时间的个体差异。病变复杂性从日本 CTO(J-CTO)评分 2.19±1.44增加至 2.46±1.28,逆行手术从 31.1%增加至 40.7%;然而,手术成功率从 87.7%提高至 92.1%。透视时间保持不变,但 AK 降低了 14.9%,从 2.35Gy(四分位距[IQR],1.29-4.14Gy)降至 2.00Gy(IQR,1.08-3.45Gy),DAP 降低了 21.5%,从 130Gy•cm²(IQR,70-241Gy•cm²)降至 102Gy•cm²(IQR,58-184Gy•cm²)。辐射暴露由病变复杂性(J-CTO 评分)和手术复杂性(顺行或逆行)决定。DRI 由透视帧率和使用的设备类型决定,但主要影响仍然是术者之间的差异。

结论

尽管病变和手术复杂性增加,但在观察期间辐射暴露仍有所降低。尽管许多术者已经达到了低辐射暴露的目标,但在辐射管理方面仍存在很大的术者间差异,表明还有进一步改进的潜力。

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