Cozzi F, Steiner M, Rosati D, Madonna L, Colarossi G
Division of Pediatric Surgery, University of Rome La Sapienza, Italy.
J Pediatr Surg. 1988 Mar;23(3):203-6. doi: 10.1016/s0022-3468(88)80722-x.
The clinical features of 41 infants with various types of nasal obstruction were reviewed to study the correlation between the degree of nasal obstruction and clinical manifestations. Twenty-one subjects had bilateral choanal atresia/stenosis; 12 had unilateral choanal atresia/stenosis, and eight who were referred with suspected choanal atresia had a simple inflammatory nasal obstruction. Patients with bilateral choanal obstruction and patients with unilateral choanal obstruction or rhinitis showed no differences in clinical picture or in referral age. Many infants with either unilateral or bilateral choanal obstruction had one or more symptoms not fully relieved after surgical repair, although the choanae were widely patent. At long-term follow-up the surviving patients showed spontaneous recovery and good nasal respiration. Overall, five patients died. Since the common syndrome appeared to be related to a dysfunction of the autonomic nervous system, we conclude that any type of nasal obstruction may exacerbate or precipitate an underlying maturational autonomic disturbance.
回顾了41例患有各种类型鼻阻塞婴儿的临床特征，以研究鼻阻塞程度与临床表现之间的相关性。21例受试者患有双侧后鼻孔闭锁/狭窄；12例患有单侧后鼻孔闭锁/狭窄，8例因疑似后鼻孔闭锁转诊的患者患有单纯性炎性鼻阻塞。双侧后鼻孔阻塞患者与单侧后鼻孔阻塞或鼻炎患者在临床表现或转诊年龄上无差异。许多单侧或双侧后鼻孔阻塞的婴儿在手术修复后，尽管后鼻孔已广泛开放，但仍有一个或多个症状未完全缓解。在长期随访中，存活患者显示出自然恢复且鼻腔呼吸良好。总体而言，5例患者死亡。由于常见综合征似乎与自主神经系统功能障碍有关，我们得出结论，任何类型的鼻阻塞都可能加重或引发潜在的成熟性自主神经紊乱。
