Iwanaga T, Koyama H, Imaoka S, Furukawa H, Hiratsuka M, Ogawa A
Dept. of Surgery, Center for Adult Diseases, Osaka.
Gan No Rinsho. 1988 Apr;34(4):442-6.
Thirty-six cases of a heterochronous cancer in the remnant stomach following a partial gastrectomy for gastric cancer have been compared with 12 cases of gastric cancer following a gastrectomy for benign diseases. Lesions of a heterochronous cancer are characteristically similar to those of a synchronous multiple gastric cancer. Patients with a heterochronous cancer were found to have high rates of synchronous multiple cancers in the resected stomach as compared with none found in gastric cancer patients following surgical operation for a benign disease. Lesions of cancer after surgery for a benign disease when found were mostly in the anastomosis of the remnant stomach. These findings suggest that a heterochronous gastric cancer may develop into lesions of multiple cancers.
对36例因胃癌行胃部分切除术后残胃发生异时性癌的病例与12例因良性疾病行胃切除术后发生胃癌的病例进行了比较。异时性癌的病变特征与同步性多原发性胃癌的病变相似。发现异时性癌患者切除胃中同步性多原发性癌的发生率较高，而因良性疾病接受手术的胃癌患者未发现同步性多原发性癌。因良性疾病手术后发现的癌灶大多位于残胃吻合处。这些发现提示异时性胃癌可能发展为多原发性癌病变。
