[A metachronous and synchronous multiple colonic cancer appearing 15 years and 3 months after resection of a synchronous multiple colonic cancer].

A case of multiple colonic cancer appearing 15 years and 3 months after the resection of a synchronous multiple colonic cancer is reported. A 65-year-old man complained of abdominal pain, abdominal fullness, and diarrhea. A barium enema revealed a so-called "apple core lesion" and a filling defect, and he was diagnosed as having a multiple colonic cancer. A subtotal colectomy was performed and he has been free of any sign of recurrence since this operation. In this case, the interval between the first and the second cancer is longer than most reported cases. Thus, as a precaution, a longer follow-up is recommended for patients with a synchronous multiple colonic cancer.