Shri Ram Murti Smarak College of Engg. & Technology, Pharmacy, Bareilly, U.P, India.
Pharmacy Academy, IFTM University, Moradabad, 244102, U.P, India.
Curr Drug Deliv. 2021;18(8):1085-1093. doi: 10.2174/1567201818666210211094727.
The polyelectrolyte complexes (PECs) are adaptable constructs shaped by electrostatic interaction between biopolymers with inverse charges. Polyelectrolyte edifices comprise an exceptional class of polymeric mixtures comprising of polyions with inverse charges, which can be charged either cationically or anionically. Significant advancement has been made in the course of recent years towards new medication conveyance frameworks. The subject of broad, essential and applied exploration covers the marvel of interpolymer collaborations and polyelectrolyte complex development. Basically, applied polyelectrolytes raise on the grounds that the advantages of supportability are perceived in the scholarly world and modern examination settings. Polyelectrolytes are a form of polymer that has endless ionizable practical arrangements. Ionized polyelectrolytes in the arrangement can form a complex with an oppositely charged particle called a polyelectrolyte complex. The review article emphasizes on PECs and their classification, characterization, as well as a critical analysis of the current research and applicability in the drug delivery technology.
聚电解质复合物（PECs）是通过带相反电荷的生物聚合物之间的静电相互作用形成的适应性构建体。聚电解质结构包含一类特殊的聚合物混合物，其中包含带相反电荷的聚离子，可以带正电荷或负电荷。近年来，在新型药物输送系统方面取得了重大进展。广泛、基础和应用研究的主题涵盖了聚合物间相互作用和聚电解质复合物形成的奥秘。实际上，由于在学术界和现代研究环境中认识到了可持续性的优势，因此应用聚电解质得到了发展。聚电解质是一种具有无限可离子化实用配置的聚合物。溶液中的离子化聚电解质可以与带相反电荷的粒子形成复合物，称为聚电解质复合物。这篇综述文章重点介绍了 PEC 及其分类、特性，以及对药物输送技术中当前研究和适用性的批判性分析。
