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妊娠期和哺乳期的精神药物使用。

Psychiatric Medication Use in Pregnancy and Breastfeeding.

机构信息

Johns Hopkins Women's Mood Disorders Center, Johns Hopkins School of Medicine, 550 North Broadway, Suite 305, Baltimore, MD 21025, USA.

出版信息

Obstet Gynecol Clin North Am. 2021 Mar;48(1):131-149. doi: 10.1016/j.ogc.2020.11.006.

Abstract

Active peripartum psychiatric illness is associated with adverse outcomes for exposed pregnancies/children. Likely due to high rates of obesity, pregnant women with psychiatric illness also have higher rates of preeclampsia, cesarean section, and gestational diabetes. Postpartum depression is associated with lower IQ, slower language development, and behavioral problems in exposed children. Discontinuing psychiatric medications for pregnancy increases risk for relapse significantly, and the postpartum time period is high risk for developing psychiatric illness. Obstetricians-gynecologists are front-line providers for psychiatric care of women during peripartum. This article provides a framework and knowledge base for management of psychiatric illness during peripartum.

摘要

围产期精神疾病与暴露于其中的妊娠/儿童的不良结局相关。可能由于肥胖率较高,患有精神疾病的孕妇还具有更高的先兆子痫、剖宫产和妊娠糖尿病的发生率。产后抑郁症与暴露儿童的智商较低、语言发育较慢和行为问题相关。怀孕期间停止精神药物治疗会显著增加疾病复发的风险,而产后时期是发生精神疾病的高风险期。妇产科医生是围产期女性精神保健的一线提供者。本文为围产期精神疾病的管理提供了一个框架和知识库。

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