Periodontology, Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, UK.
Periodontal Research Group, Institute of Clinical Sciences, College of Medical & Dental Sciences, The University of Birmingham, Birmingham, UK; Birmingham Community Healthcare NHS Trust, Birmingham, UK.
J Dent. 2021 Mar;106:103562. doi: 10.1016/j.jdent.2020.103562. Epub 2021 Feb 8.
To adapt the supranational European Federation for Periodontology (EFP) S3-Level Clinical Practice Guideline for treatment of periodontitis (stage I-III) to a UK healthcare environment, taking into account the views of a broad range of stakeholders, and patients.
This UK version is based on the supranational EFP guideline (Sanz et al., 2020) published in the Journal of Clinical Periodontology. The source guideline was developed using the S3-level methodology, which combined the assessment of formal evidence from 15 systematic reviews with a moderated consensus process of a representative group of stakeholders, and accounts for health equality, environmental factors and clinical effectiveness. It encompasses 62 clinical recommendations for the treatment of stage I-III periodontitis, based on a step-wise process mapped to the 2017 classification system.
The UK version was developed from the source guideline using a formal process called the GRADE ADOLOPMENT framework. This framework allows for the adoption (unmodified acceptance), adaptation (acceptance with modifications) and the de novo development of clinical recommendations. Using this framework and following the S3-process, the underlying systematic reviews were updated and a representative guideline group of 75 delegates from 17 stakeholder organisations was assembled into three working groups. Following the formal S3-process, all clinical recommendations were formally assessed for their applicability to the UK and adoloped accordingly.
Using the ADOLOPMENT protocol, a UK version of the EFP S3-level clinical practice guideline was developed. This guideline delivers evidence- and consensus-based clinical recommendations of direct relevance to the dental community in the UK.
The aim of S3-level guidelines is to combine the evaluation of formal evidence, grading and synthesis with the clinical expertise of a broad range of stakeholders to form clinical recommendations. Herein, the first major international S3-level guideline in dentistry, the EFP guideline, was implemented for direct clinical applicability in the UK healthcare system.
将欧洲牙周病学联合会（EFP）的跨国 S3 级临床实践指南（治疗牙周炎[I-III 期]）适应于英国医疗保健环境，同时考虑到广泛的利益相关者和患者的意见。
本英国版指南基于发表在《临床牙周病学杂志》上的跨国 EFP 指南（Sanz 等人，2020 年）。该源指南采用 S3 级方法制定，该方法将来自 15 项系统评价的正式证据评估与代表性利益相关者小组的经协调共识过程相结合，并考虑到健康平等、环境因素和临床效果。它包含了 62 项针对 I-III 期牙周炎治疗的临床建议，这些建议基于映射到 2017 年分类系统的逐步流程。
英国版指南是使用一种名为 GRADE ADOLOPMENT 框架的正式流程从源指南中开发而来。该框架允许采用（未经修改的接受）、适应（经修改的接受）和全新制定临床建议。使用该框架并遵循 S3 流程，对基础系统评价进行了更新，并召集了来自 17 个利益相关者组织的 75 名代表组成了三个工作组。在正式的 S3 流程之后，对所有临床建议进行了是否适用于英国的正式评估，并根据需要进行了制定。
使用 ADOLOPMENT 方案，制定了 EFP S3 级临床实践指南的英国版。该指南提供了与英国牙科界直接相关的基于证据和共识的临床建议。
S3 级指南的目的是将正式证据的评估、分级和综合与广泛的利益相关者的临床专业知识相结合，形成临床建议。在此，EFP 指南作为第一个主要的国际 S3 级牙科指南，在英国医疗保健系统中直接实施了临床适用性。
