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内分泌反应性乳腺癌的生育力保存:数据与偏见

Fertility preservation in endocrine responsive breast cancer: data and prejudices.

作者信息

Buonomoa Barbara, Peccatorib Fedro A

机构信息

https://orcid.org/0000-0001-9921-4639.

https://orcid.org/0000-0001-8227-8740.

出版信息

Ecancermedicalscience. 2020 Dec 18;14:1157. doi: 10.3332/ecancer.2020.1157. eCollection 2020.

Abstract

Even if current guidelines suggest an early referral of young breast cancer (BC) patients to fertility preservation counselling, physicians still lack knowledge about the different available strategies. Hormonal stimulation to harvest mature oocytes is considered unsafe by many oncologists and experts in reproductive medicine, particularly in the setting of oestrogen receptor-positive BC. The aim of this mini-review is to provide an overview on the available data about this topic in order to clarify potential misunderstandings and to highlight the new trends in the oncofertility field with their pros and limitations.

摘要

即使当前指南建议早期将年轻乳腺癌(BC)患者转诊至生育力保存咨询处,但医生们仍缺乏对不同可用策略的了解。许多肿瘤学家和生殖医学专家认为,通过激素刺激获取成熟卵母细胞是不安全的,尤其是在雌激素受体阳性乳腺癌的情况下。本综述的目的是概述有关该主题的现有数据,以澄清潜在的误解,并突出肿瘤生殖领域的新趋势及其优点和局限性。

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本文引用的文献

1
ESHRE guideline: female fertility preservation.欧洲人类生殖与胚胎学会指南:女性生育力保存
Hum Reprod Open. 2020 Nov 14;2020(4):hoaa052. doi: 10.1093/hropen/hoaa052. eCollection 2020.
4
Burning Questions in the Oncofertility Counseling of Young Breast Cancer Patients.年轻乳腺癌患者肿瘤生育咨询中的热点问题
Breast Cancer (Auckl). 2020 Sep 4;14:1178223420954179. doi: 10.1177/1178223420954179. eCollection 2020.
5
Pregnancy After Breast Cancer in Patients With Germline Mutations.遗传性突变患者的乳腺癌后妊娠。
J Clin Oncol. 2020 Sep 10;38(26):3012-3023. doi: 10.1200/JCO.19.02399. Epub 2020 Jul 16.

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