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内分泌反应性乳腺癌的生育力保存:数据与偏见

Fertility preservation in endocrine responsive breast cancer: data and prejudices.

作者信息

Buonomoa Barbara, Peccatorib Fedro A

机构信息

https://orcid.org/0000-0001-9921-4639.

https://orcid.org/0000-0001-8227-8740.

出版信息

Ecancermedicalscience. 2020 Dec 18;14:1157. doi: 10.3332/ecancer.2020.1157. eCollection 2020.

DOI:10.3332/ecancer.2020.1157
PMID:33574902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7864682/
Abstract

Even if current guidelines suggest an early referral of young breast cancer (BC) patients to fertility preservation counselling, physicians still lack knowledge about the different available strategies. Hormonal stimulation to harvest mature oocytes is considered unsafe by many oncologists and experts in reproductive medicine, particularly in the setting of oestrogen receptor-positive BC. The aim of this mini-review is to provide an overview on the available data about this topic in order to clarify potential misunderstandings and to highlight the new trends in the oncofertility field with their pros and limitations.

摘要

即使当前指南建议早期将年轻乳腺癌(BC)患者转诊至生育力保存咨询处,但医生们仍缺乏对不同可用策略的了解。许多肿瘤学家和生殖医学专家认为,通过激素刺激获取成熟卵母细胞是不安全的,尤其是在雌激素受体阳性乳腺癌的情况下。本综述的目的是概述有关该主题的现有数据,以澄清潜在的误解,并突出肿瘤生殖领域的新趋势及其优点和局限性。

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Fertility preservation in endocrine responsive breast cancer: data and prejudices.内分泌反应性乳腺癌的生育力保存:数据与偏见
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本文引用的文献

1
ESHRE guideline: female fertility preservation.欧洲人类生殖与胚胎学会指南:女性生育力保存
Hum Reprod Open. 2020 Nov 14;2020(4):hoaa052. doi: 10.1093/hropen/hoaa052. eCollection 2020.
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Reproductive Outcomes After Breast Cancer in Women With vs Without Fertility Preservation.有生育力保存的与无生育力保存的乳腺癌女性的生殖结局。
JAMA Oncol. 2021 Jan 1;7(1):86-91. doi: 10.1001/jamaoncol.2020.5957.
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Burning Questions in the Oncofertility Counseling of Young Breast Cancer Patients.年轻乳腺癌患者肿瘤生育咨询中的热点问题
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Ann Oncol. 2020 Jun;31(6):674-696. doi: 10.1016/j.annonc.2020.03.284. Epub 2020 Mar 19.
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First birth achieved after fertility preservation using vitrification of in vitro matured oocytes in a woman with breast cancer.一名乳腺癌女性通过玻璃化冷冻体外成熟卵母细胞进行生育力保存后首次成功分娩。
Ann Oncol. 2020 Apr;31(4):541-542. doi: 10.1016/j.annonc.2020.01.005. Epub 2020 Feb 18.
9
Impact of BRCA1 and BRCA2 mutations on ovarian reserve and fertility preservation outcomes in young women with breast cancer.BRCA1 和 BRCA2 突变对年轻乳腺癌女性卵巢储备和生育保存结局的影响。
J Assist Reprod Genet. 2020 Mar;37(3):709-715. doi: 10.1007/s10815-019-01658-9. Epub 2019 Dec 24.
10
Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion.接受性腺毒性治疗或性腺切除术的患者的生育力保存:委员会意见。
Fertil Steril. 2019 Dec;112(6):1022-1033. doi: 10.1016/j.fertnstert.2019.09.013.