Case Brian C, Lisko John C, Babaliaros Vasilis C, Greenbaum Adam B, Satler Lowell, Ben-Dor Itsik, Forrestal Brian J, Yerasi Charan, Kamioka Norihiko, Rogers Toby, Waksman Ron, Lederman Robert J, Khan Jaffar M
Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Structural Heart and Valve Center, Emory University Hospital, Atlanta, GA, USA.
Ann Cardiothorac Surg. 2021 Jan;10(1):172-179. doi: 10.21037/acs-2020-mv-25.
Transcatheter mitral valve replacement (TMVR) is a therapeutic option for patients with severe mitral disease who are deemed inoperable due to their overall surgical risk. The close relationships between the left ventricular outflow tract (LVOT) and the anterior mitral valve leaflet can lead to LVOT obstruction, a common complication with high mortality. Predicting and preventing LVOT obstruction is therefore essential, prior to TMVR. Laceration of the Anterior Mitral leaflet to Prevent Outflow ObtructioN (LAMPOON) is a transcatheter electrosurgical technique to split the anterior mitral valve leaflet immediately prior to TMVR. The technique has been studied in a prospective clinical trial and has evolved with many iterations for specific anatomies. In this review, we discuss the different LAMPOON techniques to prevent and treat LVOT obstruction.
经导管二尖瓣置换术(TMVR)是针对因整体手术风险而被认为无法进行手术的严重二尖瓣疾病患者的一种治疗选择。左心室流出道(LVOT)与二尖瓣前叶之间的密切关系可导致LVOT梗阻,这是一种常见且死亡率高的并发症。因此,在TMVR之前预测和预防LVOT梗阻至关重要。二尖瓣前叶撕裂以预防流出道梗阻(LAMPOON)是一种经导管电外科技术,可在TMVR之前立即劈开二尖瓣前叶。该技术已在前瞻性临床试验中进行了研究,并针对特定解剖结构进行了多次改进。在本综述中,我们讨论了预防和治疗LVOT梗阻的不同LAMPOON技术。